Associate Investigators
Prof. Dr. Heiko Heerklotz
Contact
Prof. Dr. Heiko Heerklotz
Department of Pharmaceutical Technology and Biopharmacy (Faculty of Chemistry and Pharmacy),
University of Freiburg
University of Freiburg
T +49 761 203 6338
heiko.heerklotz(at)pharmazie.uni-freiburg.de
Further Information
10 selected publications:
- Engineering asymmetric lipid vesicles: Accurate and convenient ontrol of the outer leaflet lipid composition.
Markones M, Drechsler C, Kaiser M, Kalie L, Heerklotz H, Fiedler S (2018).
Langmuir 34:1999-2005 - Biomembrane permeabilization: Statistics of individual leakage events harmonize the interpretation of vesicle leakage.
Braun S, Pokorná Š, Šachl R, Hof M, Heerklotz H, Hoernke M (2018).
ACS Nano 12:813-819 - Correlating antimicrobial activity and model membrane leakage induced by nylon-3 polymers and detergents
Hovakeemian SG, Liu R, Gellman SH, Heerklotz H (2015).
Soft Matter 11:6840-51 - Characterizing vesicle leakage by fluorescence lifetime measurements.
Patel H, Tscheka C, Heerklotz H (2009).
Soft Matter 5:2849-2851 - Monitoring detergent-mediated solubilization and reconstitution of lipid membranes by isothermal titration calorimetry.
Heerklotz H, Tsamaloukas A, Keller S (2009).
Nat Protocols 4:686-697 - Interactions of surfactants with lipid membranes.
Heerklotz H (2008).
Quarterly Reviews of Biophysics 41:205-264 - Uptake and release protocol for assessing membrane binding and permeation by way of isothermal titration calorimetry.
Tsamaloukas A, Keller S, Heerklotz H (2007).
Nat Protocols 2:695-704 - A quantitative model describing the selective solubilization of membrane domains.
Keller S, Tsamaloukas , Heerklotz H (2005).
J Am Chem Soc. 127:11469-11476 - Structural, volumetric and thermodynamic characterization of a micellar sphere-to-rod transition.
Heerklotz H, Tsamaloukas A, Kita-Tokarczyk K, Strunz P, Gutberlet T (2004).
J Am Chem Soc. 126:16544 - Triton promotes domain formation in ´lipid raft´ mixtures.
Heerklotz H (2002).
Biophys. J. 83:2693-2701