CIBSS - Centre for integrative Biological Signalling Studies CIBSS

PUBLICATIONS

CIBSS Publications

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Cutting without cleaving: How caspase-1 shapes leukemia beyond enzymatic activity

Braun LM, Zeiser R.

Cell Chem Biol. 2026; doi: 10.1016/j.chembiol.2025.12.011

Personalised multipeptide-based T-cell activator for chronic lymphocytic leukaemia: an open-label, single-centre, phase 1 study

Heitmann JS, Maringer Y, Jung S, Wacker M, Hackenbruch C, Polster M, Marconato M, Nelde A, Bauer J, Zwick M, Baur AS, Metzger A, Krolla C, Andrieux G, Köhler N, Boerries M, Denk M, Zieschang L, Kammer C, Hoenisch-Gravel N, Richter M, Oezbek MT, Wirths S, Dengler A, Dubbelaar ML, Pumptow M, Martus P, Brüggemann M, Rammensee HG, Salih HR, Walz JS.

Lancet Haematol. 2026; doi: 10.1016/S2352-3026(25)00323-0

Myelin antigen capture in the CNS by B cells expressing EBV latent membrane protein 1 leads to demyelinating lesion formation

Kim H, Schneider M, Raach Y, Karypidis P, Roux J, Perdikaris G, Holdermann S, Kulsvehagen L, Lecourt AC, Narr K, Sankowski R, Diebold M, Bartoszek-Kandler E, Kapfhammer JP, Zimmer G, Pröbstel AK, Prinz M, Kappos L, Sanderson NSR, Derfuss T.

Cell. 2026; doi: 10.1016/j.cell.2025.12.031.

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Automated identification of contextually relevant biomedical entities with grounded LLMs

Watter M, Giuliani C, Benadi G, Engel F, Binder H, Kaier K.

Sci Rep. 2026; doi: 10.1038/s41598-026-35492-8

Identification of biomedical entities from multiple repositories using a specialized metadata schema and search-augmented large language models

Kaier K, Engel F, Benadi G, Giuliani C, Watter M, Kalantari A, Schuller K, Franzke CW, Sperandio M, Binder H.

BMC Res Notes. 2026; doi: 10.1186/s13104-026-07632-w.

Gastrin for the treatment of acute graft-versus-host disease of the stomach

Gawron J, Czech M, Rückert T, Holzmüller V, Andreev G, Burk AC, Hartmann A, Chatterjee S, Andrieux G, Marquard FE, Baur AS, Stell AV, Krausz M, Braun LM, Osswald N, Melchinger W, Wertheimer T, Proano-Vasco AI, Maas-Bauer K, Schmitt-Graeff A, Boerries M, Köhler N, Ayuk FA, Schell C, Quante M, Zeiser R.

Blood. 2026; doi: 10.1182/blood.2025031080. Online ahead of print.

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Targeting β-catenin degradation with GSK3β inhibitors induces cell death in acute lymphoblastic leukemia

Cosgun KN, Jumaa H, Robinson ME, Cheng Z, Oulghazi S, Kume K, Fonseca Arce D, Agadzhanian N, Kistner KM, Leveille E, Drivet E, Yu F, Qian Z, Song JY, Chan WC, Xu L, Xiao G, Taketo MM, Kothari S, Davids MS, Schjerven H, Jellusova J, Müschen M.

Nat Cancer. 2026; doi: 10.1038/s43018-025-01093-z

Comprehensive analysis of CRISPR array repeat mutations reveals subtype-specific patterns and links to spacer dynamics

Mitrofanov A, Beisel CL, Baumdicker F, Alkhnbashi OS, Backofen R.

Microlife. 2026; doi: 10.1093/femsml/uqaf050.

CoMPaseD: advanced planning of proteomic experiments aiming to identify small proteins

Bartel J, Kaulich PT, Ferrero-Bordera B, Gelhausen R, Backofen R, Tholey A, Maaß S.

Microlife. 2026; doi: 10.1093/femsml/uqaf043.

Foxi1 regulates multipotent mucociliary progenitors and ionocyte specification through transcriptional and epigenetic mechanisms

Bowden S, Brislinger-Engelhardt MM, Hansen M, Andricek A, Temporal-Plo A, Weber D, Hägele S, Lorenz F, Litwin T, Kreutz C, Walentek P.

PLoS Biol. 2026; doi: 10.1371/journal.pbio.3003583

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