CIBSS - Centre for integrative Biological Signalling Studies CIBSS

PUBLICATIONS

CIBSS Publications

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2026
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Foxi1 regulates multipotent mucociliary progenitors and ionocyte specification through transcriptional and epigenetic mechanisms

Bowden S, Brislinger-Engelhardt MM, Hansen M, Andricek A, Temporal-Plo A, Weber D, Hägele S, Lorenz F, Litwin T, Kreutz C, Walentek P.

PLoS Biol. 2026; doi: 10.1371/journal.pbio.3003583.

LCK at the crossroad of immunodeficiency and autoimmunity: Mechanisms and therapeutic opportunities.

Woessner NM, Keller B, Minguet S.

Immunol Lett. 2026 ; doi: 10.1016/j.imlet.2025.107126.

Sparse dimensionality reduction for analyzing single-cell-resolved interactions

Brunn N, Hackenberg M, Fullio CL, Vogel T, Binder H.

Bioinformatics. 2024; doi: 10.1093/bioadv/vbaf230.

Molecular Determinants of Selective and High-affinity Binding of the Scaffold Protein PDZK1 to the Urate Transporter URAT1

Mymrikov EV, Wirth C, Heinicke JI, Goll J, Kern BA, Steck C, Iaroslavtceva AK, Mühlethaler T, Köttgen A, Hunte C.

J Mol Biol. 2026; doi: 10.1016/j.jmb.2025.169615

Somatic STAT5BN642H mutations shape variable immune landscapes resulting in heterogenous immune diseases

Grün S, Rensing-Ehl A, Suske T, Wolter-Mess J, Gehrig J, Mann J, König C, Hauri M, Heeg M, Leahy TR, Genevieve D, Gaillard JB, Broly M, Bourdin A, Castro C, Seidel L, Bengsch B, Aichele P, Weißert K, Fernandez-Orth J, Schipperges V, Andrieux G, Boerries M, Cabezas-Wallscheid N, Erlacher M, Elling R, Speckmann C, Heller L, Schulte B, Lorenz M, Schwarz K, Moriggl R, Ehl S.

J Allergy Clin Immunol. 2026; doi: 10.1016/j.jaci.2025.12.993

 

Nuclear myosin VI cooperates with actin to promote transcriptional cluster formation at androgen receptors

Jayawardana IM, Fleisch JM, Knerr J, Wang H, Holst M, Tholen S, Schilling O, Grosse R.

J Biol Chem. 2026; doi: 10.1016/j.jbc.2025.111088

Genetically Encoded SpyTag Enables Modular AAV Retargeting via SpyCatcher-Fused Ligands for Targeted Gene Delivery

Armbruster A, Hörner M, Wagner HJ, Fink-Straube C, Weber W.

ACS Synth Biol. 2026; doi: 10.1021/acssynbio.5c00565

O-(2-[18F]fluoroethyl)-L-tyrosine-PET-guided versus contrast-enhanced T1-weighted MRI-guided re-irradiation in patients with recurrent glioblastoma (GLIAA/NOA-10 ARO2013-01): a multicentre, open-label, randomised trial.

Grosu AL, Weber WA, Graf E, Mix M, Nestle U, Schimek-Jasch T, Wiehle R, Mader I, Würtemberger U, Langen KJ, Niyazi M, Paulsen F, König L, Giordano FA, Spehl I, Bernhardt D, Schymalla MM, Pöttgen C, Semrau S, Brunner T, Hültenschmidt B, Krause BJ, Ciernik IF, Beck J, Baumert BG, Meyer PT, Urbach H, Popp I; GLIAA Study Group.

Lancet Oncol. 2026; doi: 10.1016/S1470-2045(25)00642-4.

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IL-6 trans-signaling: an overlooked driver of retinal neovascularization?

Jung M, Ness JN, Schwämmle ME, Rapp J, Boneva S, Groß O, Mitschke J, Schlunck G, Agostini H, Hannibal L, Bucher F.

Angiogenesis. 2025; doi: 10.1007/s10456-025-10022-8

A Likelihood-Based Framework for Analysing Sarcomeric Protein Machinery in Cardiac Myocyte Models

Freytag J, Beyer S, Timmer J, Timmermann V.

Computing in Cardiology, 2025; Vol 52. doi: 10.22489/CinC.2025.314.

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