CIBSS - Centre for integrative Biological Signalling Studies CIBSS

PUBLICATIONS

CIBSS Publications

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A transposon-like strategy for proteins

Di Ventura B.

Nat Chem Biol. 2025; doi: 10.1038/s41589-025-01947-8.

Expanding the Inositol Pyrophosphate Toolbox: Stereoselective Synthesis and Application of PP-InsP4 Isomers in Plant Signaling

Ritter K, Braun AS, Liu G, Lu M, Gaugler V, Schaaf G, Jessen HJ.

Angew Chem Int Ed Engl. 2025; doi: 10.1002/anie.202507058. 

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Circulating Proteins for Prediction of Kidney Disease Progression and Cardiovascular Outcomes: Individual Participant Data Meta-Analysis of Four Cohorts

Lopez-Silva C, Surapaneni A, Coresh J, Chen TK, Schlosser P, Rhee EP, Waikar SS, Schmidt IM, Deo R, Ganz P, Dubin R, Ramachandran VS, Kimmel PL, Schrauben S, Parikh CR, Bonventre JV, Dobre M, Rao PS, Ricardo AC, Weir MR, Grams ME; CRIC Study Investigators.

Am J Nephrol. 2025; doi: 10.1159/000547138. Online ahead of print.

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Regulation of somatic hypermutation by higher-order chromatin structure

Schoeberl UE, Fitz J, von der Linde M, Valieris R, Bauer B, Malzl D, Froussios K, Costea J, Schmidt F, Pflaum J, Bartl B, Albrecht J, Wiedemann EM, Garcia AC, Peycheva M, Rizzi M, Goloborodko A, Tojal da Silva I, Pavri R.

Mol Cell. 2025; doi: 10.1016/j.molcel.2025.06.003

Barcoded viral tracing identifies immunosuppressive astrocyte-glioma interactions

Andersen BM, Faust Akl C, Wheeler MA, Li Z, Diebold M, Kilian M, Rone JM, Misra A, Kenison JE, Lee JH, Lee HG, Polonio CM, Merrell D, Weiss JH, Godinez L, Piester G, Illouz T, Ye JJ, Ghia A, Martinez J, Chung EN, Srun L, Farrenkopf D, Flausino LE, Schüle AM, Sanmarco LM, Giovannoni F, Fehrenbacher L, Charabati M, Gutiérrez-Vázquez C, Cusick MM, Prabhakar PS, Bossi CC, Lapinskas E, Nowarski R, Getz G, Ligon KL, Prinz M, Chiocca EA, Reardon DA, Quintana FJ.

Nature. 2025; doi: 10.1038/s41586-025-09191-9.

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γδ T Cells and Inborn Errors of Immunity

Sagar, Ehl S.

Eur J Immunol. 2025; doi: 10.1002/eji.202451457.

AhR activation mitigates graft-versus-host disease of the central nervous system by reducing microglial NF-κB signaling

Zähringer A, Morgado I, Erny D, Ingelfinger F, Gawron J, Chatterjee S, Wenger V, Schmidt D, Schwöbel L, Adams RC, Langenbach M, Hartmann A, Osswald N, Wolf J, Schlunck G, Briquez PS, Grueter K, Ruess DA, Frew I, Burk AC, Holzmüller V, Grimbacher B, Michonneau D, Andrieux G, Socié G, Kolter J, Boerries M, Follo M, Blaeschke F, Sevenich L, Prinz M, Zeiser R, Vinnakota JM.

Blood Adv. 2025; doi: 10.1182/bloodadvances.2024015000.

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Stereoselective chemoenzymatic phytate transformations provide access to diverse inositol phosphate derivatives

Häner GM, Liu G, Lange E, Jork N, Ditrich K, Greiner R, Schaaf G, Jessen HJ

Chem Sci. 2025; doi: 10.1039/d5sc02844b.

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LRBA deficiency impairs autophagy and contributes to enhanced antigen presentation and T-cell dysregulation.

Sindram E, Deau MC, Ligeon LA, Sanchez-Martin P, Nestel S, Jung S, Ruf S, Mishra P, Proietti M, Günther S, Thedieck K, Roussa E, Rambold A, Münz C, Kraft C, Grimbacher B, Gámez-Díaz L.

EMBO Rep. 2025; doi: 10.1038/s44319-025-00504-7.

MCAM is a prognostic biomarker in patients with liver cirrhosis and HCC

Stockinger E, Luxenburger H, Bettinger D, Berlin C, Obwegs D, Sagar, Sturm L, Gromak M, Gairing S J, Foerster F, Labenz C, MacNelly S, Boettler T, Holzner P, Bronsert P, Bengsch B, Thimme R, Hofmann M, Roehlen N.

Hepatol Commun. 2024 Oct 3. doi: 10.1097/HC9.0000000000000532. eCollection 2024 Oct 1.

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