Infection increases activity via Toll dependent and independent mechanisms in Drosophila melanogaster

Vincent CM, Beckwith EJ, Simoes da Silva CJ, Pearson WH, Kierdorf K, Gilestro GF, Dionne MS.

PLoS Pathog. 2022; doi: 10.1371/journal.ppat.1010826.

 

This study, a real-time tracking on a behavioural profiling platform in Drosophila melanogaster. Several systemic bacterial infections cause significant increases in physical activity, and the extent of this activity can be a predictor of survival time in some lethal infections.