Centre for Integrative Biological Signalling Studies
Cluster of Excellence, University of Freiburg


The right tune for blood


Repetitive elements trigger RIG-I-like receptors to enhance hematopoietic stem cell formation

Have a look at your own DNA!


CIBSS is taking part in the Science Days online outreach event

Common Vulnerabilities of Coronaviruses


International study in which Freiburg scientists are participating maps molecular targets for possible therapy for MERS, SARS-CoV1, and SARS-CoV2

Carbon Storage from the Lab


Researchers at the University of Freiburg established the world’s largest collection of moss species for the peat industry and science

The line of succession


An unusual mechanism of robustness in charge of brain mRNAs

“Launchpad” promotes young researchers


The Cluster of Excellence CIBSS offers a funding program to postdocs for independent research

Innate lymphoid cells regenerate within lung tissue


Researchers generate a cell atlas of lung innate lymphoid cells (ILCs) and discovered local renewal of these cells in lung tissue

A pint of home brewed science


More than 100 guests tuned in to hear talks from eight local Freiburg scientists, including two CIBSS Members, during the online Pint of Science Freiburg

Divide and enlarge


Researchers discover a mechanism that causes cell nuclei to grow

How does coronavirus leave the cell?


Microscopic analyses document an interaction between the SARS-CoV-2 virus and a specific enzyme – this could lead to potential treatments

Immunobiology in 280 characters or less


Susana Minguet and her students tweet about SARS-CoV-2

By Razor or by Chance: What a Court Decision Means for the Future of Plant Breeding


The legal scholars Elisabeth Andersen and Katharina Schreiber are interviewed about their CIBSS project on the regulation of targeted mutagenesis technologies

Mix and Match: How signalling molecules recognize their partners


Researchers develop a new method that allows them to understand how phosphatase enzymes distinguish their substrates

How immune cells activate the killer mode


Freiburg researchers find missing link in immune response

CIBSS member new Vice President of the Max Planck Society


Asifa Akhtar was elected the first female VP in the Biological-Medical Section

Wolfgang Driever elected as new EMBO Member


The developmental biologist and one of the CIBSS Speakers receives this honour for his scientific achievements in the life sciences

A prize for the CIBSS spirit


First InteGREATor award for excellent publications in integrative signalling science goes to Dr. Maximillian Hörner, Nadim Aizarani and Jelena Tosic

Controlling plant processes with light


Scientists from Freiburg and Düsseldorf develop a new optogenetic tool for use in plant research

SARS-CoV-2 hijacks the transport system and skeleton of host cells


International cooperation of researchers reveals new drug targets and a surprising cell skeleton’s involvement in SARS-CoV-2 infection

Heisenberg funding for Anne-Kathrin Classen


The German Research Foundation is funding the signalling researcher’s work at the University of Freiburg for five years

Brothers in arms: the brain and its blood vessels


Study by CIBSS Members show how blood vessels sense the metabolic state of neuronal cells

Register now for the CIBSS symposium “Signalling across Scales"


The international meeting on Signalling Studies takes place in Freiburg on November 23 to 25, 2020 or online

Closed borders and Working from home


What is the future of cross-border projects on the European Campus during the Corona crisis? Interview with CIBSS Member Prof. Dr. Wolfgang Schamel

Day of Immunology @CIBSS


Videoclips by CIBSS researchers about the immune system and vaccines

Actin: What it is and what it does in the cell


International experts met in February 2020 at the University of Freiburg to discuss new insights in the variety of cellular functions of actin

Cancer mutation in dual role


Researchers show that an oncogenic mutation in leukemia cells also promotes inflammations in the body

Homemaking for bacterial guests: A molecular softener opens the plant cells’ doors


Researchers from CIBSS found that a microtubule regulating protein plays an important role in building a symbiotic partnership that helps plants grow

Taking Synthetic Biology Tools to the Classroom


Four high school classes and a group of teachers learned about Signalling Studies in the Signalhaus.

Incentives for academic talent


German Research Foundation funds University of Freiburg program promoting young international talents in biological signalling research

Symposium: "Actin Assembly for Intracellular Functions"


International experts meet to discuss new insights in the variety of cellular functions of actin, one of the most abundant proteins inside cells.

How the immune system becomes blind to cancer cells


Researchers have described the activation of a key protein used by tumor cells to stop the body’s immune response

Launch Your Career at CIBSS


The CIBSS Launchpad initiative starts with an informal exchange with experienced researchers

Starting life with an impaired immune system


Research by CIBSS member reveals new numbers on prevalence of innate immunodeficiency in Germany: At least 2300 people are affected

„Gene of the Week“ is awarded German Science Blog Prize 2019


Theresa Schredelseker, PhD student at CIBSS, writes about genetic research for a lay audience and was now awarded the "Special Prize of the Editor" by "Wissenschaft kommuniziert".

“Creating fascinating projects to address pressing issues of our times”


A student of the iGEM-Freiburg Team 2019 writes about her experience and the team’s project “Reflect!”

Two New Consolidator Grants for CIBSS Members


The European Research Council will be funding Maja Banks-Köhn and Henning Jessen with 2 million euros each

Puzzling over cell molecules


Students in the Master Lab learn how to conduct independent research in bio-signaling studies

Marco Prinz receives Gottfried Wilhelm Leibniz Prize


German Research Foundation honours researcher from Freiburg University Medical Centre

New measurements of immune guards in the human brain


Various forms of immune cells in the human brain identified for the first time

Cellular Identity


A Freiburg research team deciphers how stem cells decide their identity

How gene expression noise shapes cell fate


Max Planck and CIBSS researcher Dominic Grün develops a method for measuring gene ex-pression noise across single cells in complex tissue.

Using Gene Scissors to Detect Diseases


Researchers present sensor prototype that can rapidly, precisely, and cost-effectively measure molecular signals for cancer

Filaments that structure DNA


Researchers discover how outside stimuli drive the formation and reorganization of the cytoskeleton in the nucleus of mammalian cells

Simplifying cell selection with antibiotics


A new method developed by CIBSS researchers makes analyzing complex molecular pathways easier

Bacterial protein impairs important cellular processes


Researchers have discovered a new function of antibiotic resistant bacteria

Fascination for the Molecules of Life


CIBSS at the Science Days

Stress in the Powerhouse of the Cell


University of Freiburg researchers discover a new principle – how cells protect themselves from mitochondrial defects

Receptor complexes on the assembly line


Researchers decipher assembly of glutamate receptors and its importance for memory formation

Local networking with global appeal


Signalling researchers meet at Lake Schluchsee for the first CIBSS retreat to discuss results and future challenges

“A very positive feeling”


Three CIBSS PhD students attended this year’s “I, Scientist” conference at the TU Berlin

“Spaghetti” gel acts like tissue


Biotechnologist Wilfried Weber is building molecular tools with which to make better treatments

A matter of concentration


Researchers are studying how proteins regulate the stem cells of plants

Passing on the fascination for research


20 students spent a day in the labs of the Signalhaus

Doorway and doorman all in one


The protein complex TOM regulates protein access to cell power plants – Chris Meisinger aims to find out which signal pathways can change that selection

Dissolving protein traffic jam at the entrance of mitochondria


Researchers from Freiburg discovered a novel mechanism that ensures obstacle-free protein traffic into the powerhouse of the cell

Epigenetischer Stopp-Schalter für therapieresistenten Prostatakrebs


Forscher des Universitätsklinikums Freiburg und der Universität Freiburg beschreiben ein neues Enzym, das die Aktivität von Genen steuert. [German Version only]

A question of time


Researchers show how the immune system distinguishes between self molecules and non-self molecules such as those from pathogens.

Not all wounds heal according to plan


Cell biologist Anne-Kathrin Classen investigates differences between normal and impaired tissue repair

Traffic control of cells


Researchers develop a hydrogel whose stiffness and permeability to cells can be controlled with light

“Cancer cells often overlook the stop signs”


Julia Jellusova investigates how metabolism influences the function of immune cells

Wie sprechen sich Zellen untereinander ab?


A feature of CIBSS is in the "Clusters of Excellence, Uni Freiburg" series of the Badische Zeitung (German version only)

Binding with consequences


Researchers from Freiburg and Ulm discover mechanism through which bacteria attack white blood cells

Scientists create new map of brain's immune system


A team of researchers under the direction of the Medical Center - University of Freiburg has created an entirely new map of the brain's own immune system in humans and mice.

An elegant mechanism


Researchers discovered a connection between metabolite and protein transport in the powerhouse of the cell

Cover Story for a Control-of-Function Technology


New publication in Chembiochem

Green revolution for grains


Cell biologist Thomas Ott aims to make food supplies securer and farming more sustainable

Velcro for human cells


Freiburg researchers engineer cellular adhesion receptors that can be controlled with light

From Understanding to Communicating in the Language of Life


A feature of CIBSS is in the current issue of the ZEIT newspaper [German version only]

Deep Learning for all


Freiburg computer scientists develop a user-friendly plug-in for the automated analysis of biomedical images

Braking and Accelerating


Maja Köhn uses biochemical tools to investigate how certain enzymes behave when the immune system meets invaders

Connecting Creative Minds


The University of Freiburg has submitted its proposal in the “Universities of Excellence” funding line

One hundred percent success


Two Clusters of Excellence for the University of Freiburg: Biological Signalling Studies and Bioinspired Materials Research