Centre for Integrative Biological Signalling Studies
Cluster of Excellence, University of Freiburg

Dr. Nora Vögtle

Dr. Nora Vögtle

Institute of Biochemistry and Molecular Biology (Faculty of Medicine),
University of Freiburg

+49 761 203 5270

CIBSS Research Project:

 

10 selected publications

  • An early mtUPR: Redistribution of the nuclear transcription factor Rox1 to Mmitochondria protects against intramitochondrial proteotoxic aggregates.
    Poveda-Huertes D, Matic S, Marada A, Habernig L, Licheva M, Myketin L, Gilsbach R, Tosal-Castano S, Papinski D, Mulica P, Kretz O, Kücükköse C, Taskin AA, Hein L, Kraft C, Büttner S, Meisinger C, Vögtle FN (2020).
    Mol Cell. 77(1):180-188
  • Mutations in PMPCB Encoding the Catalytic Subunit of the Mitochondrial Presequence Protease Cause Neurodegeneration in Early Childhood.
    Vögtle FN, Brändl B, Larson A, Pendziwiat M, Friederich MW, White SM, Basinger A, Kücükköse C, Muhle H, Jähn JA, Keminer O, Helbig KL, Delto CF, Myketin L, Mossmann D, Burger N, Miyake N, Burnett A, van Baalen A, Lovell MA, Matsumoto N, Walsh M, Yu HC, Shinde DN, Stephani U, Van Hove JLK, Müller FJ, Helbig I (2018).
    Am J Hum Genet. 102(4):557-573.
  • The novel mitochondrial matrix protease Ste23 is required for efficient presequence degradation and processing.
    Taskin AA, Kücükköse C, Burger N, Mossmann D, Meisinger C, Vögtle FN(2017).
    Mol Biol Cell. 28(8):997-1002
  • Landscape of submitochondrial protein distribution.
    Vögtle FN, Burkhart JM, Gonczarowska-Jorge H, Kücükköse C, Taskin AA, Kopczynski D, Ahrends R, Mossmann D, Sickmann A, Zahedi RP, Meisinger C (2017).
    Nat Commun. 8(1):290.
  • MIPEP recessive variants cause a syndrome of left ventricular non-compaction, hypotonia, and infantile death.
    Eldomery MK, Akdemir ZC, Vögtle FN, Charng WL, Mulica P, Rosenfeld JA, Gambin T, Gu S, Burrage LC, Al Shamsi A, Penney S, Jhangiani SN, Zimmerman HH, Muzny DM, Wang X, Tang J, Medikonda R, Ramachandran PV, Wong LJ, Boerwinkle E, Gibbs RA, Eng CM, Lalani SR, Hertecant J, Rodenburg RJ, Abdul-Rahman OA, Yang Y, Xia F, Wang MC, Lupski JR, Meisinger C, Sutton VR (2016).
    Genome Med. 8(1):106.
  • The fusogenic lipid phosphatidic acid promotes the biogenesis of mitochondrial outer membrane protein Ugo1.
    Vögtle FN, Keller M, Taskin AA, Horvath SE, Guan XL, Prinz C, Opalińska M, Zorzin C, van der Laan M, Wenk MR, Schubert R, Wiedemann N, Holzer M, Meisinger C (2015).
    J Cell Biol. 2015 Sep 14;210(6):951-60.
  • Quantitative Profiling for Substrates of the Mitochondrial Presequence Processing Protease Reveals a Set of Nonsubstrate Proteins Increased upon Proteotoxic Stress. Burkhart JM, Taskin AA, Zahedi RP, Vögtle FN (2015).
    J Proteome Res. 14(11):4550-63
  • Amyloid-β peptide induces mitochondrial dysfunction by inhibition of preprotein maturation.
    Mossmann D, Vögtle FN, Taskin AA, Teixeira PF, Ring J, Burkhart JM, Burger N, Pinho CM, Tadic J, Loreth D, Graff C, Metzger F, Sickmann A, Kretz O, Wiedemann N, Zahedi RP, Madeo F, Glaser E, Meisinger C (2014).
    Cell Metab. 20(4):662-9.
  • Intermembrane space proteome of yeast mitochondria.
    Vögtle FN, Burkhart JM, Rao S, Gerbeth C, Hinrichs J, Martinou JC, Chacinska A, Sickmann A, Zahedi RP, Meisinger C (2012).
    Mol Cell Proteomics. 11(12):1840-52.
  • Global analysis of the mitochondrial N-proteome identifies a processing peptidase critical for protein stability.
    Vögtle FN, Wortelkamp S, Zahedi RP, Becker D, Leidhold C, Gevaert K, Kellermann J, Voos W, Sickmann A, Pfanner N, Meisinger C (2009).
    Cell. 139(2):428-39.