CIBSS - Centre for integrative Biological Signalling StudiesCIBSS

Preprints (bioRxiv)

Preprints (bioRxiv)

  • Complementary Ribo-seq approaches map the translatome and provide a small protein census in the foodborne pathogen Campylobacter jejuni
    Kathrin Froschauer, Sarah L. Svensson, Rick Gelhausen, Elisabetta Fiore, Philipp Kible, Alicia Klaude, Martin Kucklick, Stephan Fuchs, Florian Eggenhofer, Susanne Engelmann, Rolf Backofen, Cynthia M. Sharma
    bioRxiv 2022.11.09.515450; doi: doi.org/10.1101/2022.11.09.515450
  • LRBA balances antigen presentation and T-cell responses by facilitating autophagy through the binding to PIK3R4 and FYCO1
    Laura Gámez-Díaz, Laura-Anne Ligeon, Elena Sindram, Marie-Celine Deau, Pablo Sanchez-Martin, Sigrun Nestel, Sophie Jung, Stefanie Ruf, Pankaj Mishra, Michele Proietti, Stefan Günther, Kathrin Thedieck, Eleni Roussa, Angelika Rambold, Christian Münz, Claudine Kraft, Bodo Grimbacher
    bioRxiv 2022.10.17.512524; doi: doi.org/10.1101/2022.10.17.512524
  • Snf1/AMPK fine-tunes TORC1 signaling in response to glucose starvation
    Marco Caligaris, Raffaele Nicastro, Zehan Hu, Farida Tripodi, Johannes Erwin Hummel, Marie-Anne Deprez, Joris Winderickx, Sabine Rospert, Paola Coccetti, Jörn Dengjel, Claudio De Virgilio
    bioRxiv 2022.10.18.512649; doi: doi.org/10.1101/2022.10.18.512649
  • Chimeric 3D-gastruloids – a versatile tool for studies of mammalian peri-gastrulation development
    Alexandra E. Wehmeyer, Katrin M. Schüle, Alexandra Conrad, Chiara M. Schröder, Simone Probst, Sebastian J. Arnold
    bioRxiv 2022.05.25.493377; doi: doi.org/10.1101/2022.05.25.493377
  • Erythrocyte invasion-neutralising antibodies prevent Plasmodium falciparum RH5 from binding to basigin-containing membrane protein complexes
    Abhishek Jamwal, Chrisina Constantin, Sebastian Henrich, Wolfgang Bildl, Bernd Fakler, Simon Draper, Uwe Schulte, Matthew K Higgins
    bioRxiv 2022.09.23.509221; doi: doi.org/10.1101/2022.09.23.509221
  • Conformational dynamics and target-dependent myristoyl switch of calcineurin B homologous protein 3
    Florian Becker, Simon Fuchs, Lukas Refisch, Friedel Drepper, Wolfgang Bildl, Uwe Schulte, Shuo Liang, Jonas Immanuel Heinicke, Sierra C. Hansen, Clemens Kreutz, Bettina Warscheid, Bernd Fakler, Evgeny V. Mymrikov, Carola Hunte
    bioRxiv 2022.09.23.509142; doi: doi.org/10.1101/2022.09.23.509142
  • A network of Notch-dependent and -independent her genes controls neural stem and progenitor cells in the zebrafish thalamic proliferation zone
    Christian E. Sigloch, Dominik Spitz, Wolfgang Driever
    bioRxiv 2022.09.15.508073; doi: doi.org/10.1101/2022.09.15.508073
  • The performance of deep generative models for learning joint embeddings of single-cell multi-omics data
    Eva Brombacher, Maren Hackenberg, Clemens Kreutz, Harald Binder, Martin Treppner
    bioRxiv 2022.06.06.494951; doi: doi.org/10.1101/2022.06.06.494951
  • Capillary electrophoresis mass spectrometry identifies new isomers of inositol pyrophosphates in mammalian tissues
    Danye Qiu, Chunfang Gu, Guizhen Liu, Kevin Ritter, Verena B. Eisenbeis, Tamara Bittner, Artiom Gruzdev, Lea Seidel, Bertram Bengsch, Stephen B. Shears, Henning J. Jessen
    bioRxiv 2022.09.14.507917; doi: doi.org/10.1101/2022.09.14.507917
  • Microglia mediate synaptic plasticity induced by 10 Hz repetitive transcranial magnetic stimulation
    Amelie Eichler, Dimitrios Kleidonas, Zsolt Turi, Maximilian Fliegauf, Matthias Kirsch, Dietmar Pfeifer, Takahiro Masuda, Marco Prinz, Maximilian Lenz, Andreas Vlachos
    bioRxiv 2021.10.03.462905; doi: doi.org/10.1101/2021.10.03.462905
  • Pseudokinase HPO-11 inhibits nonsense-mediated decay to ensure genome stability in C. elegans
    Qian Zhao, Erika D Gromoff, Wei Yang, Jennifer Schwarz, Lena Tittel, Ekkehard Schulze, Bettina Warscheid, Ralf Baumeister, Wenjing Qi
    bioRxiv 2022.09.04.506508; doi: doi.org/10.1101/2022.09.04.506508
  • Extending Janus lectins architecture: characterization and application to protocells Simona Notova, Lina Siukstaite, Francesca Rosato, Federica Vena, Aymeric Audfray, Nicolai Bovin, Ludovic Landemarre, Winfried Römer, Anne Imberty
    bioRxiv 2022.08.15.503968; doi: doi.org/10.1101/2022.08.15.503968
  • Structural principles of B-cell antigen receptor assembly
    Ying Dong, Xiong Pi, Frauke Bartels-Burgahn, Deniz Saltukoglu, Zhuoyi Liang, Jianying Yang, Yumei Zheng, Frederick W. Alt, Michael Reth, Hao Wu
    bioRxiv 2022.08.13.503858; doi: doi.org/10.1101/2022.08.13.503858
  • Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism
    Claudio Bussi, Tiaan Heunis, Enrica Pellegrino, Elliott M. Bernard, Nourdine Bah, Mariana Silva dos Santos, Pierre Santucci, Beren Aylan, Angela Rodgers, Antony Fearns, Julia Mitschke, Christopher Moore, James I. MacRae, Maria Greco, Thomas Reinheckel, Matthias Trost, Maximiliano G. Gutierrez
    bioRxiv 2022.08.09.503288; doi: doi.org/10.1101/2022.08.09.503288
  • Gene expression noise dynamics unveil functional heterogeneity of ageing hematopoietic stem cells
    Reyna Edith Rosales-Alvarez, Jasmin Rettkowski, Josip Stefan Herman, Gabrijela Dumbović, Nina Cabezas-Wallscheid, Dominic Grün
    bioRxiv 2022.08.04.502776; doi: doi.org/10.1101/2022.08.04.502776
  • Reliability and accuracy of single-molecule FRET studies for characterization of structural dynamics and distances in proteins
    Ganesh Agam, Christian Gebhardt, Milana Popara, Rebecca Mächtel, Julian Folz, Benjamin Ambrose, Neharika Chamachi, Sang Yoon Chung, Timothy D. Craggs, Marijn de Boer, Dina Grohmann, Taekjip Ha, Andreas Hartmann, Jelle Hendrix, Verena Hirschfeld, Christian G. Hübner, Thorsten Hugel, Dominik Kammerer, Hyun-Seo Kang, Achillefs N. Kapanidis, Georg Krainer, Kevin Kramm, Edward Lemke, Eitan Lerner, Emmanuel Margeat, Kristen Martens, Jens Michaelis, Jaba Mitra, Gustavo G. Moya Muñoz, Robert Quast, Nicole B. Robb, Michael Sattler, Michael Schlierf, Jonathan Schneider, Tim Schröder, Anna Sefer, Piau Siong Tan, Johann Thurn, Philip Tinnefeld, John van Noort, Shimon Weiss, Nicolas Wendler, Niels Zijlstra, Anders Barth, Claus A. M. Seidel, Don C. Lamb, Thorben Cordes
    bioRxiv 2022.08.03.502619; doi: doi.org/10.1101/2022.08.03.502619
  • Soluble amyloid-β precursor peptide does not regulate GABAB receptor activity
    Pascal Dominic Rem, Vita Sereikaite, Diego Fernandez-Fernandez, Sebastian Reinartz, Daniel Ulrich, Thorsten Fritzius, Luca Trovò, Salome Roux, Ziyang Chen, Philippe Rondard, Jean-Philippe Pin, Jochen Schwenk, Bernd Fakler, Martin Gassmann, Tania R. Barkat, Kristian Strømgaard, Bernhard Bettler
    bioRxiv 2022.08.02.502499; doi: doi.org/10.1101/2022.08.02.502499
  • Quantitative real-time in-cell imaging reveals heterogeneous clusters of proteins prior to condensation
    Chenyang Lan, Juhyeong Kim, Svenja Ulferts, Fernando Aprile-Garcia, Abhinaya Anandamurugan, Robert Grosse, Ritwick Sawarkar, Aleks Reinhardt, Thorsten Hugel
    bioRxiv 2022.08.01.502196; doi: doi.org/10.1101/2022.08.01.502196
  • Eya-controlled affinity between cell lineages drives tissue self-organization during Drosophila oogenesis Vanessa Weichselberger, Patrick Dondl, Anne-Kathrin Classen
    bioRxiv 2022.07.28.501863; doi: doi.org/10.1101/2022.07.28.501863
  • A deeply conserved protease, acylamino acid-releasing enzyme (AARE), acts in plant ageing Sebastian N.W. Hoernstein, Buğra Özdemir, Nico van Gessel, Alessandra A. Miniera, Bruno Rogalla von Bieberstein, Lars Nilges, Joana Schweikert Farinha, Ramona Komoll, Stella Glauz, Tim Weckerle, Friedrich Scherzinger, Marta Rodriguez-Franco, Stefanie J. Müller-Schüssele, Ralf Reski
    bioRxiv 2022.05.18.492440; doi: doi.org/10.1101/2022.05.18.492440
  • TREK-1 knock-down in human atrial fibroblasts leads to a myofibroblastic phenotype: a role in phenoconversion and over-view of mechano-sensitive channel mRNA expression in cardiac diseases Elisa Darkow, Dilmurat Yusuf, Sridharan Rajamani, Rolf Backofen, Peter Kohl, Ursula Ravens, Rémi Peyronnet
    bioRxiv 2022.07.21.492231; doi: doi.org/10.1101/2022.07.21.492231
  • Slow integrin-dependent migration organizes networks of tissue-resident mast cells Sarah K. Bambach, Lukas Kaltenbach, Nadim Aizarani, Paloma Martzloff, Alina Gavrilov, Katharina M. Glaser, Roland Thünauer, Michael Mihlan, Manuel Stecher, Aude Thiriot, Stephan Wienert, Ulrich von Andrian, Marc Schmidt-Supprian, Claus Nerlov, Frederick Klauschen, Axel Roers, Marc Bajénoff, Dominic Grün, Tim Lämmermann
    bioRxiv 2022.07.19.500614; doi: doi.org/10.1101/2022.07.19.500614
  • An accessible infrastructure for artificial intelligence using a docker-based Jupyterlab in Galaxy Anup Kumar, Gianmauro Cuccuru, Björn Grüning, Rolf Backofen
    bioRxiv 2022.07.08.499333; doi: doi.org/10.1101/2022.07.08.499333
  • Transcellular progression of infection threads in Medicago truncatula roots is controlled by locally confined cell wall modifications Chao Su, Guofeng Zhang, Marta Rodriguez-Franco, Jenny Wietschorke, Pengbo Liang, Wei Yang, Leonard Uhler, Xia Li, Thomas Ott
    bioRxiv 2022.07.07.499094; doi: doi.org/10.1101/2022.07.07.499094
  • A Physcomitrella PIN protein acts in spermatogenesis and sporophyte abortion Volker M. Lüth, Christine Rempfer, Oliver Herzog, Melanie Roecker, Marion Braun, Eva L. Decker, Ralf Reski
    bioRxiv 2022.07.05.498815; doi: doi.org/10.1101/2022.07.05.498815
  • Bilateral JNK activation is a hallmark of interface contractility and promotes elimination of aberrant cells Deepti Prasad, Katharina Illek, Friedericke Fischer, Kathrin Holstein, Anne-Kathrin Classen
    bioRxiv 2022.06.20.496791; doi: doi.org/10.1101/2022.06.20.496791
  • Shared enhancer gene regulatory networks between wound and oncogenic programs Swann Floc’hlay, Ramya Balaji, Valerie Christiaens, Carmen Bravo González-Blas, Seppe De Winter, Gert Hulselmans, Maxime De Waegeneer, Xiaojiang Quan, Duygu Koldere, Mardelle Atkins, Georg Halder, Anne Classen, Stein Aerts
    bioRxiv 2022.06.17.496596; doi: doi.org/10.1101/2022.06.17.496596
  • RPG acts as a central determinant for infectosome formation and cellular polarization during intracellular rhizobial infections
    Beatrice Lace, Chao Su, Daniel Invernot Perez, Marta Rodriguez-Franco, Tatiana Vernié, Morgane Batzenschlager, Sabrina Egli, Cheng-Wu Liu, Thomas Ott
    bioRxiv 2022.06.03.494689; doi: doi.org/10.1101/2022.06.03.494689
  • The performance of deep generative models for learning joint embeddings of single-cell multi-omics data
    Eva Brombacher, Maren Hackenberg, Clemens Kreutz, Harald Binder, Martin Treppner
    bioRxiv 2022.06.06.494951; doi: doi.org/10.1101/2022.06.06.494951
  • Mutual repression between JNK/AP-1 and JAK/STAT stratifies cell behaviors during tissue regeneration Janhvi Jaiswal, Raphael Engesser, Andrea Armengol Peyroton, Vanessa Weichselberger, Carlo Crucianelli, Isabelle Grass, Jens Timmer, Anne-Kathrin Classen
    bioRxiv 2022.05.11.491445; doi: doi.org/10.1101/2022.05.11.491445
  • Chimeric 3D-gastruloids – a versatile tool for studies of mammalian peri-gastrulation development
    Alexandra E. Wehmeyer, Katrin M. Schüle, Alexandra Conrad, Chiara M. Schröder, Simone Probst, Sebastian J. Arnold
    bioRxiv 2022.05.25.493377; doi: doi.org/10.1101/2022.05.25.493377
  • COR27/28 Regulate the Evening Transcriptional Activity of the RVE8-LNK1/2 Circadian Complex
    Maria L. Sorkin, Shin-Cheng Tzeng, Andrés Romanowski, Nikolai Kahle, Rebecca Bindbeutel, Andreas Hiltbrunner, Marcelo J. Yanovsky, Bradley S. Evans, Dmitri A. Nusinow
    bioRxiv 2022.05.16.492168; doi: doi.org/10.1101/2022.05.16.492168
  • Neuro-immune Crosstalk in the Enteric Nervous System from Early Postnatal Development to Adulthood
    Viola Maria Francesca, Chavero-Pieres Marta, Modave Elodie, Stakenborg Nathalie, Delfini Marcello, Naomi Fabre, Iris Appeltans, Tobie Martens, Katy Vandereyken, Jens Van Herck, Philippe Petry, Simon Verheijden, Sebastiaan De Schepper, Alejandro Sifrim, Katrin Kierdorf, Marco Prinz, Pieter Vanden Berghe, Thierry Voet, Guy Boeckxstaens
    bioRxiv 2022.05.12.491517; doi: doi.org/10.1101/2022.05.12.491517
  • Plasma membrane topography governs the three-dimensional dynamic localization of IgM B cell receptor clusters
    Deniz Saltukoglu, Bugra Özdemir, Michael Holtmannspötter, Ralf Reski, Jacob Piehler, Rainer Kurre, Michael Reth
    bioRxiv 2022.04.29.489661; doi: doi.org/10.1101/2022.04.29.489661
  • Kidins220 regulates the development of B cells bearing the λ light chain
    Anna-Maria Schaffer, Gina J. Fiala, Miriam Hils, Eriberto Noel Natali, Lmar Babrak, Laurenz A. Herr, Marta Rizzi, Enkelejda Miho, Wolfgang Schamel, Susana Minguet
    bioRxiv 2022.04.04.486937; doi: doi.org/10.1101/2022.04.04.486937
  • Donor strand complementation, isopeptide bonds and glycosylation reinforce highly resilient archaeal thread filaments
    Matthew C. Gaines, Michail N. Isupov, Shamphavi Sivabalasarma, Risat Ul Haque, Mathew McLaren, Patrick Tripp, Alexander Neuhaus, Vicki Gold, Sonja-Verena Albers, Bertram Daum
    bioRxiv 2022.04.26.489512; doi: doi.org/10.1101/2022.04.26.489512
  • The bacterial lectin LecA from P. aeruginosa alters membrane organization by dispersing ordered domains
    Taras Sych, Ramin Omidvar, Rafael Ostmann, Thomas Schubert, Annette Brandel, Ludovic Richert, Yves Mely, Josef Madl, Winfried Römer
    bioRxiv 2022.04.17.488572; doi: doi.org/10.1101/2022.04.17.488572
  • Multiphasic calcium signatures in the cytosol and nucleus of Lotus japonicus roots unlock the early discrimination of fungal signals
    Filippo Binci, Jürgen Kleine-Vehn, Marco Giovannetti, Lorella Navazio
    bioRxiv 2022.04.13.487819; doi: doi.org/10.1101/2022.04.13.487819
  • In macrophages fatty acid oxidation spares glutamate for use in diverse metabolic pathways required for alternative activation
    Nikki van Teijlingen Bakker, Lea Flachsman, Gustavo E. Carrizo, David E. Sanin, Simon Lawless, Angela Castoldi, Lauar Monteiro, Agnieszka M. Kabat, Mai Matsushita, Fabian Haessler, Annette Patterson, Ramon Klein Geltink, David O’Sullivan, Erika L. Pearce, Edward J. Pearce
    bioRxiv 2022.04.13.487890; doi: doi.org/10.1101/2022.04.13.487890
  • Kidins220 promotes thymic iNKT cell development by reducing TCR signals, but enhances TCR signals in splenic iNKT cells
    Laurenz A. Herr, Gina J. Fiala, Anna-Maria Schaffer, Katrin Raute, Rubí M.-H. Velasco Cárdenas, Jonas F. Hummel, Karolina Ebert, Yakup Tanriver, Susana Minguet, Wolfgang W. Schamel
    bioRxiv 2022.04.05.487104; doi: doi.org/10.1101/2022.04.05.487104
  • Breast cancer stem cell-derived tumors escape from γδ T cell immunosurveillance in vivo by modulating γδ T cell ligands
    Katrin Raute, Juliane Strietz, Geoffroy Andrieux, Oliver S. Thomas, Klaus M. Kistner, Marina Zintchenko, Peter Aichele, Houjiang Zhou, Wilfried Weber, Melanie Boerries, Mahima Swamy, Jochen Maurer, Susana Minguet
    bioRxiv 2022.04.04.486931; doi: doi.org/10.1101/2022.04.04.486931
  • Inferring kinetic rate constants from single-molecule FRET trajectories – a blind benchmark of kinetic analysis tools
    Markus Götz, Anders Barth, Søren S.-R. Bohr, Richard Börner, Jixin Chen, Thorben Cordes, Dorothy A. Erie, Christian Gebhardt, Mélodie C.A.S. Hadzic, George L. Hamilton, Nikos S. Hatzakis, Thorsten Hugel, Lydia Kisley, Don C. Lamb, Carlos de Lannoy, Chelsea Mahn, Dushani Dunukara, Dick de Ridder, Hugo Sanabria, Julia Schimpf, Claus A.M. Seidel, Roland K.O. Sigel, Magnus Berg Sletfjerding, Johannes Thomsen, Leonie Vollmar, Simon Wanninger, Keith R. Weninger, Pengning Xu, Sonja Schmid
    bioRxiv 2021.11.23.469671; doi: doi.org/10.1101/2021.11.23.469671
  • Remorin proteins serves as membrane topology scaffolds in plants
    Chao Su, Marta Rodriguez-Franco, Beatrice Lace, Nils Nebel, Casandra Hernandez-Reyes, Pengbo Liang, Eija Schulze, Claudia Popp, Jean Keller, Cyril Libourel, Alexandra A.M. Fischer, Katharina E. Gabor, Evgeny V. Mymrikov, Nikolas M. Gross, Eric Mark, Carola Hunte, Wilfried Weber, Petra Wendler, Thomas Stanislas, Pierre-Marc Delaux, Oliver Einsle, Thomas Ott
    bioRxiv 2022.03.15.484384; doi: doi.org/10.1101/2022.03.15.484384
  • Base editing derived models of human WDR34 and WDR60 disease alleles replicate retrograde IFT and hedgehog signaling defects and suggest disturbed Golgi protein transport
    Dinu Antony, Elif Yýlmaz Güleç, Zeineb Bakey, Isabel Schüle, Gwang-Jin Kim, Ilona Skatulla, Han G. Brunner, Sebastian J. Arnold, Miriam Schmidts
    bioRxiv 2022.03.14.483768; doi: doi.org/10.1101/2022.03.14.483768
  • Arabidopsis PFA-DSP-type phosphohydrolases target specific inositol pyrophosphate messengers
    Philipp Gaugler, Robin Schneider, Guizhen Liu, Danye Qiu, Jonathan Weber, Jochen Schmid, Nikolaus Jork, Markus Häner, Kevin Ritter, Nicolás Fernández-Rebollo, Ricardo F.H. Giehl, Minh Nguyen Trung, Ranjana Yadav, Dorothea Fiedler, Verena Gaugler, Henning J. Jessen, Gabriel Schaaf, Debabrata Laha
    bioRxiv 2022.03.01.482514; doi: doi.org/10.1101/2022.03.01.482514
  • Resident T cells orchestrate adipose tissue remodeling in a site peripheral to infection
    Agnieszka M. Kabat, Alexandra Hackl, David E. Sanin, Patrice Zeis, Katarzyna M. Grzes, Francesc Baixauli, Ryan Kyle, George Caputa, Joy Edwards-Hicks, Matteo Villa, Nisha Rana, Jonathan D. Curtis, Angela Castoldi, Jovana Cupovic, Leentje Dreesen, Maria Sibilia, J. Andrew Pospisilik, Joseph F. Urban Jr, Dominic Grün, Erika L. Pearce, Edward J. Pearce
    bioRxiv 2022.02.24.481701; doi: doi.org/10.1101/2022.02.24.481701
  • Tyrosine kinase inhibitors trigger lysosomal damage-associated cell lysis to activate the NLRP3 inflammasome
    Emilia Neuwirt, Giovanni Magnani, Tamara Ćiković, Anna Kostina, Svenja Wöhrle, Stephan Flemming, Larissa Fischer, Nora J. Fischenich, Benedikt S. Saller, Oliver Gorka, Steffen Renner, Claudia Agarinis, Christian Parker, Andreas Boettcher, Christopher J. Farady, Rolf Backofen, Marta Rodriguez-Franco, Martina Tholen, Thomas Reinheckel, Thomas Ott, Christina J. Groß, Philipp J. Jost, Olaf Groß
    bioRxiv 2022.02.19.480941; doi: doi.org/10.1101/2022.02.19.480941
  • A pore-forming β-trefoil lectin with specificity for the tumor-related glycosphingolipid Gb3
    Simona Notova, François Bonnardel, Francesca Rosato, Lina Siukstaite, Jessica Schwaiger, Nicolai Bovin, Annabelle Varrot, Winfried Römer, Frédérique Lisacek, Anne Imberty
    bioRxiv 2022.02.10.479907; doi: doi.org/10.1101/2022.02.10.479907
  • ZBTB18 inhibits SREBP-dependent fatty acid synthesis by counteracting CTBPs and KDM1A/LSD1 activity in glioblastoma
    R. Ferrarese, A. Izzo, G. Andrieux, S. Lagies, J.P. Bartmuss, A.P. Masilamani, A. Wasilenko, D. Osti, S. Faletti, R. Schulzki, Y. Shuai, E. Kling, V. Ribecco, D.H. Heiland, S.G. Tholen, M. Prinz, G. Pelicci, B. Kammerer, M. Börries, M.S. Carro
    bioRxiv 2020.04.17.046268; doi: doi.org/10.1101/2020.04.17.046268
  • Protein homeostasis is maintained by proteasomes containing PSMB9 induced by EEF1A2 upon mitochondrial stress
    Minji Kim, Lukasz Samluk, Tomasz Maciej Stępkowski, Ida Suppanz, Remigiusz Adam Serwa, Agata Kodroń, Bettina Warscheid, Agnieszka Chacinska
    bioRxiv 2021.12.23.473808; doi: doi.org/10.1101/2021.12.23.473808
  • Synuclein alpha accumulation mediates podocyte injury in Fabry nephropathy
    A Abed, F Braun, D Sellung, M Woidy, O Eikrem, N Wanner, K von Cossel, N Muschol, SW Gersting, AC Muntau, O Kretz, B Najafian, C Tøndel, M Mauer, T Bork, F Grahammer, W Liang, T Eierhoff, W Römer, HP Marti, VG Puelles, C Schell, TB Huber
    bioRxiv 2021.12.17.473164; doi: doi.org/10.1101/2021.12.17.473164

  • OptoAssay – Light-controlled Dynamic Bioassay Using Optogenetic Switches Nadine Urban, Maximillian Hörner, Wilfried Weber, Can Dincer
    bioRxiv 2021.11.06.467572; doi: doi.org/10.1101/2021.11.06.467572
  • Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease
    E Schäffner, JM Edgar, M Lehning, J Strauß, M Bosch-Queralt, P Wieghofer, SA Berghoff, M Krueger, M Morawski, T Reinert, W Möbius, A Barrantes-Freer, M Prinz, DS Reich, A Flügel, C. Stadelmann, R Fledrich, RM Stassart, KA Nave
    bioRxiv 2021.11.11.468223; doi: doi.org/10.1101/2021.11.11.468223
  • Requirements for mammalian promoters to decode transcription factor dynamics
    Enoch B. Antwi, Yassine Marrakchi, Özgün Çiçek, Thomas Brox, Barbara Di Ventura
    bioRxiv 2021.10.12.464037; doi: doi.org/10.1101/2021.10.12.464037
  • Microglia mediate synaptic plasticity induced by 10 Hz repetitive magnetic stimulation
    Amelie Eichler, Dimitrios Kleidonas, Zsolt Turi, Matthias Kirsch, Dietmar Pfeifer, Takahiro Masuda, Marco Prinz, Maximilian Lenz, Andreas Vlachos
    bioRxiv 2021.10.03.462905; doi: doi.org/10.1101/2021.10.03.462905
  • Accumulation of the GSK3 target protein β-catenin is lethal for B cell precursors and malignant B cells
    Huda Jumaa, Klaus M. Kistner, Corinna Setz, M. Mark Taketo, Hassan Jumaa, Julia Jellusova
    bioRxiv 2021.09.17.460779; doi: doi.org/10.1101/2021.09.17.460779
  • Infection increases activity via Toll dependent and independent mechanisms in Drosophila melanogaster
    Crystal M. Vincent, Esteban J. Beckwith, William H. Pearson, Katrin Kierdorf, Giorgio Gilestro, Marc S. Dionne
    bioRxiv 2021.08.24.457493; doi: doi.org/10.1101/2021.08.24.457493
  • Integrated annotation and analysis of genomic features reveal new types of functional elements and large-scale epigenetic phenomena in the developing zebrafish
    Damir Baranasic, Matthias Hörtenhuber, Piotr Balwierz, Tobias Zehnder, Abdul Kadir Mukarram, Chirag Nepal, Csilla Varnai, Yavor Hadzhiev, Ada Jimenez-Gonzalez, Nan Li, Joseph Wragg, Fabio D’Orazio, Noelia Díaz, Benjamín Hernández-Rodríguez, Zelin Chen, Marcus Stoiber, Michaël Dong, Irene Stevens, Samuel E. Ross, Anne Eagle, Ryan Martin, Pelumi Obasaju, Sepand Rastegar, Alison C. McGarvey, Wolfgang Kopp, Emily Chambers, Dennis Wang, Hyejeong R. Kim, Rafael D. Acemel, Silvia Naranjo, Maciej Lapinski, Vanessa Chong, Sinnakaruppan Mathavan, Bernard Peers, Tatjana Sauka-Spengler, Martin Vingron, Piero Carninci, Uwe Ohler, Scott Allen Lacadie, Shawn Burgess, Cecilia Winata, Freek van Eeden, Juan M. Vaquerizas, José Luis Gómez-Skarmeta, Daria Onichtchouk, Ben James Brown, Ozren Bogdanovic, Monte Westerfield, Fiona C. Wardle, Carsten O. Daub, Boris Lenhard, Ferenc Müller
    bioRxiv 2021.08.09.454869; doi: doi.org/10.1101/2021.08.09.454869 
  • Engineered chimeric T cell receptor fusion construct (TRuC)-expressing T cells prevent translational shutdown in SARS-CoV-2-infected cells
    Ira Godbole, Kevin Ciminski, O. Sascha Yousefi, Salma Pathan-Chhatbar, Deniz Saltukoglu, Niklas Vesper, Pavel Salavei, Juliane Strietz, Nicole Gensch, Michael Reth, Martin Schwemmle, Wolfgang W. Schamel
    bioRxiv 2021.06.25.449871; doi: https://doi.org/10.1101/2021.06.25.449871
  • Spindle position dictates division site during asymmetric cell division in moss Elena Kozgunova, Mari W. Yoshida, Ralf Reski, Gohta Goshima
    bioRxiv 2020.03.03.975557; doi: doi.org/10.1101/2020.03.03.975557
  • Integrated phospho-proteogenomic and single-cell transcriptomic analysis of meningiomas establishes robust subtyping and reveals subtype-specific immune invasion
    Christina Blume, Helin Dogan, Lisa Schweizer, Matthieu Peyre, Sophia Doll, Daniel Picard, Roman Sankowski, Volker Hovestadt, Konstantin Okonechnikov, Philipp Sievers, Areeba Patel, David Reuss, Mirco Friedrich, Damian Stichel, Daniel Schrimpf, Katja Beck, Hans-Georg Wirsching, Gerhard Jungwirth, C Oliver Hanemann, Katrin Lamszus, Manfred Westphal, Nima Etminan, Andreas Unterberg, Christian Mawrin, Marc Remke, Olivier Ayrault, Peter Lichter, Stefan M Pfister, Guido Reifenberger, Michael Platten, Till Milde, David TW Jones, Rachel Grossmann, Zvi Ram, Miriam Ratliff, Christel Herold-Mende, Jan-Philipp Mallm, Marian C Neidert, Wolfgang Wick, Marco Prinz, Michael Weller, Matthias Mann, Michel Kalamarides, Andreas von Deimling, Matthias Schlesner, Felix Sahm
    bioRxiv 2021.05.11.443369; doi: doi.org/10.1101/2021.05.11.443369
  • Targeting cancer glycosylation repolarizes tumor-associated macrophages allowing effective immune checkpoint blockade
    Michal A. Stanczak, Natalia Rodrigues Mantuano, Nicole Kirchhammer, David E. Sanin, Jinyu Wang, Marcel P. Trefny, Gianni Monaco, Melissa A. Gray, Adam Petrone, Abhishek S. Kashyap, Katharina Glatz, Benjamin Kasenda, Karl Normington, James Broderick, Li Peng, Oliver M.T. Pearce, Erika L. Pearce, Carolyn R. Bertozzi, Alfred Zippelius, Heinz Läubli
    bioRxiv 2021.04.11.439323; doi: doi.org/10.1101/2021.04.11.439323
  • Medium optimization for biomass production of three peat moss (Sphagnum L.) species using fractional factorial design and response surface methodology
    Melanie A. Heck, Ingrida Melková, Clemens Posten, Eva L. Decker, Ralf Reski
    bioRxiv 2021.03.19.436135; doi: doi.org/10.1101/2021.03.19.436135
  • GraphProt2: A graph neural network-based method for predicting binding sites of RNA-binding proteins
    Michael Uhl, Van Dinh Tran, Florian Heyl, Rolf Backofen
    bioRxiv 850024; doi: doi.org/10.1101/850024
  • Spatiotemporal heterogeneity of glioblastoma is dictated by microenvironmental interference
    Vidhya M. Ravi, Paulina Will, Jan Kueckelhaus, Na Sun, Kevin Joseph, Henrike Salié, Jasmin von Ehr, Lea Vollmer, Jasim K. Benotmane, Nicolas Neidert, Marie Follo, Florian Scherer, Jonathan M Goeldner, Simon P. Behringer, Pamela Franco, Ulrich G. Hofmann, Christian Fung, Jürgen Beck, Roman Sankowski, Marco Prinz, Saskia Killmer, Bertram Bengsch, Axel Karl Walch, Daniel Delev, Oliver Schnell, Dieter Henrik Heiland
    bioRxiv 2021.02.16.431475; doi: doi.org/10.1101/2021.02.16.431475
  • A hetero-oligomeric remorin-receptor complex regulates plant developmen
    Nikolaj B. Abel, Corinna A. Buschle, Casandra Hernandez-Ryes, Sandy S. Burkart, Anne-Flore Deroubaix, Julia Mergner, Julien Gronnier, Iris K. Jarsch, Jessica Folgmann, Karl Heinz Braun, Emmanuelle Bayer, Véronique Germain, Paul Derbyshire, Frank L.H. Menke, Birgit Kemmerling, Cyril Zipfel, Bernhard Küster, Sébastien Mongrand, Macarena Marín, Thomas Ott
    bioRxiv 2021.01.28.428596; doi: doi.org/10.1101/2021.01.28.428596
  • Lineage and Spatial Mapping of Glioblastoma-associated Immunity
    Vidhya M. Ravi, Nicolas Neidert, Paulina Will, Kevin Joseph, Julian P. Maier, Jan Kückelhaus, Lea Vollmer, Jonathan M Goeldner, Simon P. Behringer, Florian Scherer, Melanie Boerries, Marie Follo, Tobias Weiss, Daniel Delev, Julius Kernbach, Pamela Franco, Nils Schallner, Christine Dierks, Maria Stella Carro, Ulrich G. Hofmann, Christian Fung, Jürgen Beck, Roman Sankowski, Marco Prinz, Oliver Schnell, Dieter Henrik Heiland
    bioRxiv 2020.06.01.121467; doi: doi.org/10.1101/2020.06.01.121467
  • G3BP1 tethers the TSC complex to lysosomes and suppresses mTORC1 in the absence of stress granules
    Mirja T. Prentzell, Ulrike Rehbein, Marti Cadena Sandoval, Ann-Sofie De Meulemeester, Ralf Baumeister, Laura Brohée, Bianca Berdel, Mathias Bockwoldt, Bernadette Carroll, Andreas von Deimling, Constantinos Demetriades, Gianluca Figlia, Alexander M. Heberle, Ines Heiland, Birgit Holzwarth, Lukas A. Huber, Jacek Jaworski, Katharina Kern, Andrii Kopach, Viktor I. Korolchuk, Ineke van ’t Land-Kuper, Matylda Macias, Mark Nellist, Stefan Pusch, Michele Reil, Anja Reintjes, Friederike Reuter, Chloë Scheldeman, Eduard Stefan, Aurelio Teleman, Omar Torres-Quesada, Saskia Trump, Peter de Witte, Teodor Yordanov, Christiane A. Opitz, Kathrin Thedieck
    bioRxiv 2020.04.16.044081; doi: doi.org/10.1101/2020.04.16.044081
  • Active fatty acid oxidation defines the cellular response towards reactive oxygen species
    Lars Kaiser, Isabel Quint, René Csuk, Manfred Jung, Hans-Peter Deigner
    bioRxiv 2020.07.13.200022; doi: doi.org/10.1101/2020.07.13.200022
  • Ex vivo detection of SARS-CoV-2-specific CD8+ T cells: rapid induction, prolonged contraction, and formation of functional memory
    Isabel Schulien, Janine Kemming, Valerie Oberhardt, Katharina Wild, Lea M. Seidel, Saskia Killmer, Sagar, Franziska Daul, Marilyn Salvat Lago, Annegrit Decker, Hendrik Luxenburger, Benedikt Binder, Dominik Bettinger, Oezlem Sogukpinar, Siegbert Rieg, Marcus Panning, Daniela Huzly, Martin Schwemmle, Georg Kochs, Cornelius F. Waller, Alexandra Nieters, Daniel Duerschmied, Florian Emmerich, Henrik Mei, Axel Schulz, Sian Llewellyn-Lacey, David A. Price, Tobias Boettler, Bertram Bengsch, Robert Thimme, Maike Hofmann, Christoph Neumann-Haefelin
    bioRxiv 2020.08.13.249433; doi: doi.org/10.1101/2020.08.13.249433
  • Hierarchical coupling between ATP hydrolysis and Hsp90’s client binding site
    Steffen Wolf, Benedikt Sohmen, Björn Hellenkamp, Johann Thurn, Gerhard Stock, Thorsten Hugel
    bioRxiv 2020.02.15.950725; doi: doi.org/10.1101/2020.02.15.950725
  • ADA2 is a lysosomal DNase regulating the type-I interferon response
    Ole Kristian Greiner-Tollersrud, Vincent Boehler, Eva Bartok, Máté Krausz, Aikaterini Polyzou, Johanna Schepp, Maximilian Seidl, Jan Ole Olsen, Cristian R. Smulski, Salvatore Raieli, Katrin Hübscher, Eirini Trompouki, Regina Link, Hilmar Ebersbach, Honnappa Srinivas, Martine Marchant, Dieter Staab, Danilo Guerini, Sebastian Baasch, Philipp Henneke, Georg Kochs, Gunther Hartmann, Roger Geiger, Bodo Grimbacher, Max Warncke, Michele Proietti
    bioRxiv 2020.06.21.162990; doi: doi.org/10.1101/2020.06.21.162990
  • ITPK1-Dependent Inositol Polyphosphates Regulate Auxin Responses in Arabidopsis thaliana
    Nargis Parvin Laha, Yashika Walia Dhir, Ricardo F.H. Giehl, Eva Maria Schäfer, Philipp Gaugler, Zhaleh Haghighat Shishavan, Hitika Gulabani, Haibin Mao, Ning Zheng, Nicolaus von Wirén, Henning J. Jessen, Adolfo Saiardi, Saikat Bhattacharjee, Debabrata Laha, Gabriel Schaaf
    bioRxiv 2020.04.23.058487; doi: doi.org/10.1101/2020.04.23.058487
  • A changing signaling environment induces multiciliated cell trans-differentiation during developmental remodeling
    Alexia Tasca, Martin Helmstädter, Magdalena Brislinger, Maximilian Haas, Peter Walentek
    bioRxiv 2020.04.16.045401; doi: doi.org/10.1101/2020.04.16.0454015
  • Approximate k-nearest neighbors graph for single-cell Hi-C dimensional reduction with MinHash
    Joachim Wolff, Rolf Backofen, Björn Grüning
    bioRxiv 2020.03.05.978569; doi: doi.org/10.1101/2020.03.05.978569
  • FreiPose: A Deep Learning Framework for Precise Animal Motion Capture in 3D Spaces
    Christian Zimmermann, Artur Schneider, Mansour Alyahyay, Thomas Brox, Ilka Diester
    bioRxiv 2020.02.27.967620; doi: doi.org/10.1101/2020.02.27.967620
  • Same Equilibrium. Different Kinetics. Protein Functional Consequences
    Sonja Schmid, Thorsten Hugel
    bioRxiv 838938; doi: doi.org/10.1101/838938
  • Complementary functions of the mechanosensitive factors egr1, klf2b and klf2a instruct the endocardial program
    Nathalie Faggianelli-Conrozier, Aikaterini Polyzou, Renee Chow, Stéphane Roth, Eirini Trompouki, Julien Vermot
    bioRxiv 718643; doi: doi.org/10.1101/718643
  • Phytochromes measure photoperiod in Brachypodium
    Mingjun Gao, Feng Geng, Cornelia Klose, Anne-Marie Staudt, He Huang, Duy Nguyen, Hui Lan, Todd C. Mockler, Dmitri A. Nusinow, Andreas Hiltbrunner, Eberhard Schäfer, Philip A. Wigge, Katja E. Jaeger
    bioRxiv 697169; doi: doi.org/10.1101/697169

 

Former preprints, already published now

  • PILS proteins provide a homeostatic feedback on auxin signaling output
    Elena Feraru, Mugurel I. Feraru, Jeanette Moulinier-Anzola, Maximilian Schwihla, Jonathan Ferreira Da Silva Santos, Lin Sun, Sascha Waidmann, Barbara Korbei, Jürgen Kleine-Vehn
    Development. 2022; doi: 10.1242/dev.200929
  • Loop detection using Hi-C data with HiCExplorer
    Joachim Wolff, Rolf Backofen, Björn Grüning
    Gigascience. 2022; doi: 10.1093/gigascience/giac061
  • 3D pose estimation enables virtual head-fixation in freely moving rats
    Artur Schneider, Christian Zimmermann, Mansour Alyahyay, Florian Steenbergen, Thomas Brox, Ilka Diester
    Neuron. 2022; doi: 10.1016/j.neuron.2022.04.019
  • The lectin LecB induces patches with basolateral characteristics at the apical membrane to promote Pseudomonas aeruginosa host cell invasion
    Roland Thuenauer, Katja Kühn, Yubing Guo, Fruzsina Kotsis, Maokai Xu, Anne Trefzer, Silke Altmann, Sarah Wehrum, Najmeh Heshmatpour, Brian Faust, Alessia Landi, Britta Diedrich, Jörn Dengjel, E. Wolfgang Kuehn, Anne Imberty, Winfried Römer
    mBio. 2022; doi: 10.1128/mbio.00819-22
  • Experimental characterization of in silico red-shift predicted iLOVL470T/Q489K and iLOVV392K/F410V/A426S mutants
    Pierre Wehler, Daniel Armbruster, Andreas Günter, Erik Schleicher, Barbara Di Ventura, Mehmet Ali Öztürk
    ACS Omega. 2022; doi: 10.1021/acsomega.2c01283
  • Selective endocytosis controls slit diaphragm maintenance and dynamics
    Konrad Lang, Julian Milosavljevic, Helena Heinkele, Mengmeng Chen, Lea Gerstner, Dominik Spitz, Séverine Kayser, Martin Helmstädter, Gerd Walz, Michael Köttgen, Andrew Spracklen, John Poulton, Tobias Hermle
    Elife. 2022; doi: 10.7554/eLife.79037
  • B cells discriminate HIV-1 Envelope protein affinities by sensing antigen binding association rates
    Md. Alamgir Hossain, Kara Anasti, Brian Watts, Kenneth Cronin, Advaiti Pai Kane, R.J. Edwards, David Easterhoff, Jinsong Zhang, Wes Rountree, Yaneth Ortiz, Laurent Verkoczy, Michael Reth, S. Munir Alam
    Cell Rep. 2022; doi: 10.1016/j.celrep.2022.111021
  • BlotIt - Optimal alignment of western blot and qPCR experiments
    Svenja Kemmer, Severin Bang, Marcus Rosenblatt, Jens Timmer, Daniel Kaschek
    PLoS One. 2022; doi: 10.1371/journal.pone.0264295
  • patcHwork: A user-friendly pH sensitivity analysis web server for protein sequences and structures
    Mirko Schmitz, Anne Schultze, Raimonds Vanags, Karsten Voigt, Barbara Di Ventura, Mehmet Ali Öztürk
    Nucleic Acids Res. 2022; doi: 10.1093/nar/gkac252
  • The endoplasmic reticulum membrane protein complex localizes to the mitochondrial - endoplasmic reticulum interface and its subunits modulate phospholipid biosynthesis in Trypanosoma brucei
    Advaitha Iyer, Moritz Niemann, Mauro Serricchio, Caroline E. Dewar, Silke Oeljeklaus, Luce Farine, Bettina Warscheid, André Schneider, Peter Bütikofer
    PLoS Pathog. 2022; doi: 10.1371/journal.ppat.1009717
  • Ethylene augments root hypoxia tolerance through amelioration of reactive oxygen species and growth cessation
    Zeguang Liu, Sjon Hartman, Hans van Veen, Hongtao Zhang, Hendrika A.C.F. Leeggangers, Shanice Martopawiro, Femke Bosman, Florian de Deugd, Peng Su, Maureen Hummel, Tom Rankenberg, Kirsty L. Hassall, Julia Bailey-Serres, Frederica L. Theodoulou, Laurentius A.C.J. Voesenek, Rashmi Sasidharan
    Plant Physiol. 2022; doi: 10.1093/plphys/kiac245. Online ahead of print.
  • Pluripotency factors determine gene expression repertoire at zygotic genome activation
    Meijiang Gao, Marina Veil, Marcus Rosenblatt, Aileen Julia Riesle, Anna Gebhard, Helge Hass, Lenka Buryanova, Lev Y. Yampolsky, Björn Grüning, Sergey V. Ulianov, Jens Timmer, Daria Onichtchouk
    Nat Commun. 2022; doi: 10.1038/s41467-022-28434-1
  • Temporal control of the integrated stress response by a stochastic molecular switch
    Philipp Klein, Stefan M. Kallenberger, Hanna Roth, Karsten Roth, Thi Bach Nga Ly-Hartig, Vera Magg, Janez Aleš, Soheil Rastgou Talemi, Yu Qiang, Steffen Wolf, Olga Oleksiuk, Roma Kurilov, Barbara Di Ventura, Ralf Bartenschlager, Roland Eils, Karl Rohr, Fred A. Hamprecht, Thomas Höfer, Oliver T. Fackler, Georg Stoecklin, Alessia Ruggieri
    Sci Adv. 2022; doi: 10.1126/sciadv.abk2022
  • Process engineering of biopharmaceutical production in moss bioreactors via model-based description and evaluation of phytohormone impact
    Natalia Ruiz-Molina, Juliana Parsons, Sina Schroeder, Clemens Posten, Ralf Reski, Eva L. Decker
    Front Bioeng Biotechnol. 2022; doi: 10.3389/fbioe.2022.837965
  • Unexpected arabinosylation after humanization of plant protein N-glycosylation
    Lennard L. Bohlender, Juliana Parsons, Sebastian N. W. Hoernstein, Nina Bangert, Fernando Rodríguez-Jahnke, Ralf Reski, Eva L. Decker
    Front Bioeng Biotechnol. 2022; doi: 10.3389/fbioe.2022.838365
  • p166 links membrane and intramitochondrial modules of the trypanosomal tripartite attachment complex Bernd Schimanski, Salome Aeschlimann, Sandro Käser, Maria Gomez-Fabra Gala, Nora Vögtle, André Schneider
    PLoS Pathog. 2022; doi: 10.1371/journal.ppat.1010207.
  • Photoaffinity capture compounds to profile the Magic Spot Nucleotide interactomes
    Thomas M. Haas, Benoît-Joseph Laventie, Simon Lagies, Caroline Harter, Isabel Prucker, Danilo Ritz, Raspudin Saleem Batcha, Danye Qiu, Wolfgang Hüttel, Jennifer Andexer, Urs Jenal, Henning J. Jessen
    Angew Chem Int Ed Engl. 2022; doi: 10.1002/anie.202201731
  • Endocytic Trafficking Promotes Vacuolar Enlargements for Fast Cell Expansion Rates in Plants
    Kai Dünser, Maria Schöller, Christian Löfke, Nannan Xiao, Barbora Pařízková, Stanislav Melnik, Eva Stöger, Ondřej Novák, Jürgen Kleine-Vehn
    Elife. 2022; doi: 10.7554/eLife.75945
  • Regulating peroxisome-ER contacts via the ACBD5-VAPB tether by FFAT motif phosphorylation and GSK3β
    Suzan Kors, Christian Hacker, Chloe Bolton, Renate Maier, Lena Reimann, Emily J.A. Kitchener, Bettina Warscheid, Joseph L. Costello, Michael Schrader
    J Cell Biol. 2022; doi: 10.1083/jcb.202003143
  • Characterisation of a highly diverged mitochondrial ATP synthase peripheral stalk subunit b in Trypanosoma brucei
    Caroline E. Dewar, Silke Oeljeklaus, Bettina Warscheid, André Schneider
    J Biol Chem. 2022; doi: 10.1016/j.jbc.2022.101829
  • Integration of A Nitrate-Related Signaling Pathway in Rhizobia-Induced Responses During Interactions with Non-Legume Host Arabidopsis thaliana
    Sebastian T. Schenk, Elisabeth Lichtenberg, Jean Keller, Pierre-Marc Delaux, Thomas Ott
    Mol Plant Microbe Interact. 2022; doi: 10.1094/MPMI-10-21-0261-R
  • Regulation of immune receptor kinases plasma membrane nanoscale landscape by a plant peptide hormone and its receptors
    Julien Gronnier, Christina M. Franck, Martin Stegmann, Thomas A. DeFalco, Alicia Abarca, Michelle Von Arx, Kai Dünser, Wenwei Lin, Zhenbiao Yang, Jürgen Kleine-Vehn, Christoph Ringli, Cyril Zipfel
    Elife. 2022; doi: 10.7554/eLife.74162.
  • Mistargeting of hydrophobic mitochondrial proteins activates a nucleus-mediated posttranscriptional quality control pathway in trypanosomes
    Caroline E. Dewar, Silke Oeljeklaus, Jan Mani, Wignand W. D. Mühlhäuser, Bettina Warscheid, André Schneider
    Nat Commun. 2022; doi: 10.1038/s41467-022-30748-z
  • A common framework of monocyte-derived macrophage activation
    David E. Sanin, Yan Ge, Emilija Marinkovic, Agnieszka M. Kabat, Angela Castoldi, George Caputa, Katarzyna M. Grzes, Jonathan D. Curtis, Sebastian Willenborg, Stefanie Dichtl, Susanne Reinhardt, Andreas Dahl, Erika L. Pearce, Sabine A. Eming, Alexander Gerbaulet, Axel Roers, Peter J. Murray, Edward J. Pearce
    Sci Immunol. 2022; doi: 10.1126/sciimmunol.abl7482.
  • RiboReport - Benchmarking tools for ribosome profiling-based identification of open reading frames in bacteria
    Rick Gelhausen, Teresa Müller, Sarah L. Svensson, Omer Alkhnbashi, Cynthia M. Sharma, Florian Eggenhofer, Rolf Backofen
    Brief Bioinform. 2022; doi: 10.1093/bib/bbab549.
  • A synthetic protein as efficient multitarget regulator against complement over-activation
    Natalia Ruiz-Molina, Juliana Parsons, Madeleine Müller, Sebastian N.W Hoernstein, Lennard L. Bohlender, Steffen Pumple, Peter F. Zipfel, Karsten Häffner, Ralf Reski, Eva L. Decker
    Commun Biol. 2022; doi: 10.1038/s42003-022-03094-5.
  • Transcriptome-wide in vivo mapping of cleavage sites for the compact cyanobacterial ribonuclease E reveals insights into its function and substrate recognition
    Ute A. Hoffmann, Florian Heyl, Said N. Rogh, Thomas Wallner, Rolf Backofen, Wolfgang R. Hess, Claudia Steglich, Annegret Wilde
    Nucleic Acids Res. 2021; doi: 10.1093/nar/gkab1161
  • The molecular appearance of native TRPM7 channel complexes identified by high-resolution proteomics
    Astrid Kollewe, Vladimir Chubanov, Fong Tsuen Tseung, Alexander Haupt, Catrin Swantje Müller, Wolfgang Bildl, Uwe Schulte, Annette Nicke, Bernd Fakler, Thomas Gudermann
    Elife. 2021; doi: 10.7554/eLife.68544
  • DNA sequence-dependent positioning of the linker histone in a nucleosome: a single-pair FRET study
    Madhura De, Mehmet Ali Öztürk, Sebastian Isbaner, Katalin Tóth, Rebecca C. Wade
    Biophys J. 2021; doi: 10.1016/j.bpj.2021.07.012
  • Kappa but not delta or mu opioid receptors form homodimers at low membrane densities
    Kristina Cechova, Chenyang Lan, Matus Macik, Nicolas P. F. Barthes, Manfred Jung, Maximilian H. Ulbrich
    Cell Mol Life Sci. 2021; doi: 10.1007/s00018-021-03963-y
  • Quantitative proteomics identifies the universally conserved ATPase Ola1p as a positive regulator of heat shock response in Saccharomyces cerevisiae
    Stefan Dannenmaier, Christine Desroches Altamirano, Lisa Schüler, Ying Zhang, Johannes Hummel, Silke Oeljeklaus, Hans-Georg Koch, Sabine Rospert, Simon Alberti, Bettina Warscheid
    J Biol Chem. 2021; doi: 10.1016/j.jbc.2021.101050
  • Quantitative Proteomics Identifies PTP1B as Modulator of B Cell Antigen Receptor Signaling
    Jennifer J. Schwarz, Lorenz Grundmann, Thomas Kokot, Kathrin Kläsener, Sandra Fotteler, David Medgyesi, Maja Köhn, Michael Reth, Bettina Warscheid
    Life Sci Alliance. 2021; doi: 10.26508/lsa.202101084
  • Autophosphorylation of the KaiC-like protein ArlH inhibits oligomerisation and interaction with ArlI, the motor ATPase of the archaellum
    J. Nuno de Sousa Machado, Leonie Vollmar, Julia Schimpf, Paushali Chaudhury, Rashmi Kumariya, Chris van der Does, Thorsten Hugel, Sonja-Verena Albers
    Mol Microbiol. 2021; doi: 10.1111/mmi.14781
  • Expanding the SiMPl plasmid toolbox for use with spectinomycin/streptomycin
    Navaneethan Palanisamy, Jara Ballestin Ballestin, Barbara Di Ventura
    ACS Omega. 2021; doi: 10.1021/acsomega.1c00649.
  • Piezo1 and BKCa channels in human atrial fibroblasts: interplay and remodelling in atrial fibrillation Dorothee Jakob, Alexander Klesen, Benoit Allegrini, Elisa Darkow, Diana Aria, Ramona Emig, Ana Simon Chica, Eva A. Rog-Zielinska, Tim Guth, Friedhelm Beyersdorf, Fabian A. Kari, Susanne Proksch, Stéphane N. Hatem, Matthias Karck, Stephan R Künzel, Hélène Guizouarn, Constanze Schmidt, Peter Kohl, Ursula Ravens, Rémi Peyronnet
    J Mol Cell Cardiol. 2021; doi: 10.1016/j.yjmcc.2021.05.002
  • Function of the HYDROXYCINNAMOYL-CoA:SHIKIMATE HYDROXYCINNAMOYL TRANSFERASE is evolutionarily conserved in embryophytes
    Lucie Kriegshauser, Samuel Knosp, Etienne Grienenberger, Kanade Tatsumi, Desirée D. Gütle, Iben Sørensen, Laurence Herrgott, Julie Zumsteg, Jocelyn K.C. Rose, Ralf Reski, Danièle Werck-Reichhart, Hugues Renault
    Plant Cell. 2021; doi: 10.1093/plcell/koab044.
  • ITPK1 is an InsP6/ADP phosphotransferase that controls systemic phosphate homeostasis in Arabidopsis
    Esther Riemer, Debabrata Laha, Robert K. Harmel, Philipp Gaugler, Verena Pries, Michael Frei, Mohammad-Reza Hajirezaei, Nargis P. Laha, Lukas Krusenbaum, Robin Schneider, Henning J. Jessen, Adolfo Saiardi, Dorothea Fiedler, Gabriel Schaaf, Ricardo F.H. Giehl
    Mol Plant. 2021; doi: 10.1016/j.molp.2021.07.011/li>
  • Protein manipulation using single copies of short peptide tags in cultured cells and in Drosophila melanogaster
    M. Alessandra Vigano, Clara-Maria Ell, Manuela MM Kustermann, Gustavo Aguilar, Shinya Matsuda, Ning Zhao, Timothy J Stasevich, George Pyrowolakis, Markus Affolter
    Development. 2021; doi: 10.1242/dev.191700
  • CRISPRidentify: identification of CRISPR arrays using machine learning approach
    Alexander Mitrofanov, Omer S. Alkhnbashi, Sergey A. Shmakov, Kira S. Makarova, Eugene V. Koonin, Rolf Backofen
    Nucleic Acids Res. 2021; doi: 10.1093/nar/gkaa1158.
  • CEDAR, an online resource for the reporting and exploration of complexome profiling data
    Joeri van Strien, Alexander Haupt, Uwe Schulte, Hans-Peter Braun, Alfredo Cabrera-Orefice, Jyoti S. Choudhary, Felix Evers, Erika Fernandez-Vizarra, Sergio Guerrero-Castillo, Taco W.A. Kooij, Petra Páleníková, Mercedes Pardo, Cristina Ugalde, Ilka Wittig, Lars Wöhlbrand, Ulrich Brandt, Susanne Arnold, Martijn A. Huynen
    Biochim Biophys Acta Bioenerg. 2021; doi: 10.1016/j.bbabio.2021.148411.
  • A secreted endoribonuclease ENDU-2 from the soma protects germline immortality in C. elegans
    Wenjing Qi, Erika D v. Gromoff, Fan Xu, Qian Zhao, Wei Yang, Dietmar Pfeifer, Wolfgang Maier, Lijiang Long, Ralf Baumeister
    Nat Commun. 2021; doi: 10.1038/s41467-021-21516-6.
  • Molecular basis of F-actin regulation and sarcomere assembly via myotilin
    Julius Kostan, Miha Pavšič, Vid Puž, Thomas C. Schwarz, Friedel Drepper, Sibylle Molt, Melissa Ann Graewert, Claudia Schreiner, Sara Sajko, Peter F.M. van der Ven, Dmitri I. Svergun, Bettina Warscheid, Robert Konrat, Dieter O. Fürst, Brigita Lenarčič, Kristina Djinović-Carugo
    PLoS Biol. 2021; doi: 10.1371/journal.pbio.3001148
  • The Gb3-enriched CD59/flotillin plasma membrane domain regulates host cell invasion by Pseudomonas aeruginosa
    Annette Brandel, Sahaja Aigal, Simon Lagies, Manuel Schlimpert, Anika Lehmann, Daniel Hummel, Daniel Fisch, Ana Valeria Meléndez, Josef Madl, Thorsten Eierhoff, Bernd Kammerer, Winfried Römer
    Cell Mol Life Sci. 2021; doi: 10.1007/s00018-021-03766-1
  • BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity
    Zsófia A. Bittner, Xiao Liu, Sangeetha Shankar, Ana Tapia-Abellán, Hubert Kalbacher, Liudmila Andreeva, Matthew Mangan, Peter Düwell, Marta Lovotti, Karlotta Bosch, Sabine Dickhöfer, Ana Marcu, Stefan Stevanović, Franziska Herster, Markus W. Löffler, Olaf-Oliver Wolz, Nadine A. Schilling, Jasmin Kümmerle-Deschner, Samuel Wagner, Anita Delor, Bodo Grimbacher, Hao Wu, Eicke Latz, Alexander N. R. Weber
    J Exp Med. 2021; doi: 10.1084/jem.20201656
  • Vaccine-induced ICOS+CD38+ cTfh are sensitive biosensors of age-related changes in inflammatory pathways
    Ramin Sedaghat Herati, Luisa Victoria Silva, Laura A. Vella, Alexander Muselman, Cecile Alanio, Bertram Bengsch, Raj K. Kurupati, Senthil Kannan, Sasikanth Manne, Andrew V. Kossenkov, David H. Canaday, Susan A. Doyle, Hildegund C.J. Ertl, Kenneth E. Schmader, E. John Wherry
    Cell Rep Med. 2021; doi: 10.1016/j.xcrm.2021.100262
  • The active repertoire of Escherichia coli peptidoglycan amidases varies with physiochemical environment
    Elizabeth A. Mueller, Abbygail G. Iken, Mehmet Ali Öztürk, Mirko Schmitz, Barbara Di Ventura, Petra Anne Levin
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