CIBSS - Centre for integrative Biological Signalling Studies CIBSS

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CIBSS Publications

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Molecular mechanism of ultrafast transport by plasma membrane Ca2+-ATPases

Vinayagam D, Sitsel O, Schulte U, Constantin CE, Oosterheert W, Prumbaum D, Zolles G, Fakler B, Raunser S.

Nature. 2025; doi: 10.1038/s41586-025-09402-3

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The microbial metabolite desaminotyrosine protects against graft-versus-host disease via mTORC1 and STING-dependent intestinal regeneration

Göttert S, Thiele Orberg E, Fan K, Heinrich P, Matthe DM, Khalid O, Klostermeier L, Suriano C, Strieder N, Gebhard C, Vonbrunn E, Mamilos A, Hirsch D, Meedt E, Kleigrewe K, Hiergeist A, Schwarz A, Gläsner J, Ghimire S, Joachim L, Voll F, Neuhaus K, Janssen KP, Perl M, Pielmeier F, Ruland J, Kreutz M, Weber D, Schmidl C, Köhler N, Tschurtschenthaler M, Hoffmann P, Edinger M, Wolff D, Bassermann F, Rehli M, Haller D, Evert M, Hildner K, Büttner-Herold M, Herr W, Gessner A, Heidegger S, Holler E, Poeck H.

Nat Commun. 2025; doi: 10.1038/s41467-025-65180-6.

AIstain: Enhancing microglial phagocytosis analysis through deep learning

Zähringer A, Vinnakota JM, Wertheimer T, Saalfrank P, Follo M, Ingelfinger F, Zeiser R.

Cell Rep Methods. 2025; doi: 10.1016/j.crmeth.2025.101207.

SDF2 and SDF2L1 are essential co-factors of DNAJB11 for Polycystin-1 processing

Busch T, Neubauer B, Sediq S, Zeisler PC, Tholen S, Schilling O, Westermann L, Köttgen M.

J Biol Chem. 2025; doi: 10.1016/j.jbc.2025.110823

Human brain slice cultures: translational applications and ethical considerations

Joseph K, Vasilikos I, Grauvogel J, Shah MJ, Reinacher PC, Nakagawa JM, Häussler U, Straehle J, Neidert NN, Fistouris P, Schneider M, Sloan SA, Weiss T, Coenen VA, Schnell O, Vlachos A, Prinz M, Hofmann UG, Beck J, Kellmeyer P, Ravi VM.

Life Sci Alliance. 2025; doi: 10.26508/lsa.202403160

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Artificial intelligence-based analysis and diagnosis of intradural extramedullary spinal tumors by stimulated Raman histology

Scheffler P, Neidert N, Straehle J, Erny D, Prinz M, Hubbe U, Rölz R, Heiland DH, Beck J, El Rahal A.

Neurooncol Adv. 2025; doi: 10.1093/noajnl/vdaf211

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The small bacterial membrane protein YohP induces nucleoid condensation in E. coli and inhibits oligomerization of antimicrobial peptides

Natriashvili A, Mohammadsadeghi N, Smudde E, Berghoff B, Ulbrich MH, Koch HG.

Microlife. 2025; doi: 10.1093/femsml/uqaf030.

High-Throughput Synthesis and Screening of a Cyanimide Library Identifies Selective Inhibitors of ISG15-Specific Protease mUSP18

Kooij R, Pol V, Gan J, van Doodewaerd BR, Sapmaz A, Campos Alonso M, Fritz G, Knobeloch KP, Geurink PP.

Angew Chem Int Ed Engl. 2025; doi: 10.1002/anie.202510941.

Multi-level expression profiling of cardiac and musculoskeletal Schwann cells in young and old mice

Haider S, Stefanovska D, Sassu E, Domisch C, Hossfeld M, Iaconianni P, Perez-Feliz S, Schneider-Warme F, Kohl P, Preissl S, Hortells L.

J Mol Cell Cardiol. 2025; doi: 10.1016/j.yjmcc.2025.10.001

A deep learning-enabled toolkit for the 3D segmentation of ventricular cardiomyocytes

Greiner J, Frangiamore F, Sonak F, Madl J, Seidel T, Kohl P, Rog-Zielinska EA.

J Physiol. 2025; doi: 10.1113/JP288557. Online ahead of print

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