CIBSS - Centre for integrative Biological Signalling Studies CIBSS

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IgD from atypical-like memory B cells and plasma cells targets commensal and environmental antigens

Tachó-Piñot R, Bashour H, Filipska M, Corral-Vazquez C, Guzman M, Marcos-Fa X, Martinuzzi D, Honner H, Canales Herrerias P, Tejedor Vaquero S, Sáez Gordón A, Perera-Bel J, Domínguez Barragán J, Arcos-Ribas B, de Campos-Mata L, Slabodkin A, Chernigovskaya M, Rodríguez de la Concepción ML, Gutierrez-Marcos J, García-García A, Nascimento Osorio A, Pascal M, Yagüe J, Juan M, Aróstegui JI, Hijano Esqué R, Sánchez Font A, Ehl S, Grimbacher B, Rizzi M, Dotta L, Chen K, Badolato R, Alsina L, Mehandru S, Cunningham-Rundles C, Carrillo J, Magri G, Greiff V, Cerutti A.

J Exp Med. 2026; doi: 10.1084/jem.20251752

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How interdiction of inositol pyrophosphate catabolism perturbs the fission yeast response to phosphate starvation

Babor J, Sanchez AM, Prucker I, Jessen HJ, Schwer B, Shuman S.

Nucleic Acids Res. 2026; doi: 10.1093/nar/gkag352.

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Blockage of autophagy causes severe skeletal muscle disruption in a mouse model for myofibrillar myopathy 6

Filippi K, Graf-Riesen K, Kuppusamy M, Unger A, Kimura K, Matijass M, Baeta H, Podlacha M, Haertter D, Kudin AP, Wiemann M, Węgrzyn G, Kornblum C, Reimann J, Linke WA, Huesgen PF, Kunz WS, Fleischmann BK, Hesse M.

Nat Commun. 2026; doi: 10.1038/s41467-026-71749-6.

 

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STAT3 isoform dynamics reveal robust splice ratio maintenance across cytokine-activated human immune cells

Ott N, Grimbacher B, Andreani V.

Front Immunol. 2026; doi: 10.3389/fimmu.2026.1792173

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CNS border macrophages in health and disease

Fliegauf M, Amann L, Prinz M.

J Immunol. 2026; doi: 10.1093/jimmun/vkaf308.

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A transcriptomic microglia taxonomy across mouse and human pathologies

Chhatbar C, Sankowski R, Schulz M, Shimizu T, Schwabenland M, Staszewski O, Scheiwe C, Nessler S, Borst K, Dumas AA, Trost E, Berchtold D, Brandão W, Mossad O, Dalmau Gasull A, Frosch M, Erny D, Diebold M, Guffart E, Ternka K, Guranda M, Vinnakota JM, Friesen M, Ouk K, Waltl I, LaMorte M, Hammond TR, Di Liberto G, Vincenti I, Kreutzfeldt M, Mughrabi IT, Al-Abed Y, Blank T, Meyer-Luehmann M, Crow YJ, Hagen N, Ofengeim D, Zeiser R, Kettwig M, Gärtner J, Meisel A, Schwemmle M, Kalinke U, Beck J, Bengsch B, Thimme R, Butovsky O, Seredenina T, Ransohoff RM, Quintana FJ, Kierdorf K, Merkler D, Stadelmann C, Priller J, Prinz M.

Nat Immunol. 2026; doi: 10.1038/s41590-026-02472-z.

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Gateways for myeloid cell entry into the central nervous system

Amann L, Prinz M.

Neuron. 2026; doi: 10.1016/j.neuron.2026.04.001. 

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Distinct origins and niches determine the cellular responsiveness of CNS macrophages after repopulation

Fliegauf M, Levard D, Cardamone F, Frosch M, Kuhn S, Sankowski R, Provinciali M, Dumas AA, Dalmau Gasull A, Aktories P, Oschwald A, Schwabenland M, Scholz R, Beyer MD, Neher JJ, Kollefrath M, Baltas D, Reichardt W, von Elverfeldt D, Vivien D, Cupovic J, Iovino N, Rubio M, Amann L, Prinz M.

Nat Immunol. 2026; doi: 10.1038/s41590-026-02457-y

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Quality of Life of Patients With Multi-Organ Autoimmune Disease and Its Relationship to Patient-Centered Care: Protocol for a Longitudinal Cohort Study

Bayrhuber M, Schlett C, Slesaczeck J, Herbst S, Mueller G, Nieters A, Grimbacher B, Farin-Glattacker E.

JMIR Res Protoc. 2026; doi: 10.2196/77786

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Proteomics Analysis of Plasma for Risk of Sepsis: Findings from the Atherosclerosis Risk in Communities Study

Ishigami J, Hu X, Schlosser P, Austin TR, Chen J, Psaty BM, Dowdy D, Ballantyne CM, Grams ME, Coresh J, Floyd JS, Matsushita K.

J Appl Lab Med. 2026; doi: 10.1093/jalm/jfaf179.

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