Orchestration of phosphate homeostasis by the ITPK1-type inositol 2 phosphate kinase in the liverwort Marchantia polymorpha

Naga Jyothi Pullagurla, Supritam Shome, Guizhen Liu, Henning J. Jessen, Debabrata Laha
Plant Physiology, https://doi.org/10.1093/plphys/kiae454

Identification and Characterization of a Blood−Brain BarrierPenetrant Inositol Hexakisphosphate Kinase (IP6K) Inhibitor

Tyler Heitmann, Gangling Liao, Glen Ernst, Michael Poslusney, Thomas van Kralingen, Ye Li, Megan Masi, Michael DePasquale, Ingrid Buchler, Huijun Wei, Gregory V. Carr, Evgeny Shlevkov, Mengsi Lu, Henning Jessen, and James C. Barrow*

https://doi.org/10.1021/acs.jmedchem.4c00190

Mitochondrial complexome and import network

Fabian den Brave, Uwe Schulte, Bernd Fakler, Nikolaus Pfanner, and Thomas Becker

Trends in Cell Biology, July 2024, https://doi.org/10.1016/j.tcb.2023.10.004

Activities and genetic interactions of fission yeast Aps1, a Nudix- type inositol pyrophosphatase and inorganic polyphosphatase

Shreya Ghosh, Ana M. Sanchez, Beate Schwer, Isabel Prucker, Nikolaus Jork, Henning J. Jessen, Stewart Shuman

mBio. 2024; https://doi.org/10.1128/mbio.01084

DYRK1A signalling synchronizes the mitochondrial import pathways for metabolic rewiring

Adinarayana Marada, CorvinWalter, Tamara Suhm, Sahana Shankar, Arpita Nandy, Tilman Brummer,  Ines Dhaouadi, F.-Nora Vögtle & Chris Meisinger.

https://doi.org/10.1038/s41467-024-49611-4

Oncogenic Calreticulin Induces Immune Escape by Stimulating TGF-β Expression and Regulatory T Cell Expansion in the Bone Marrow Microenvironment

Schmidt D, Endres C, Hoefflin R, Andrieux G, Zwick M, Karantzelis N, Staehle HF, Vinnakota JM, Duquesne S, Mozaffari Jovein M, Pfeifer D, Becker H, Blazar BR, Zähringer A, Duyster J, Brummer T, Boerries M, Baumeister J, Shoumariyeh K, Li J, Green AR, Heidel FH, Tirosh I, Pahl HL, Leimkühler N, Köhler N, de Toledo MAS, Koschmieder S, Zeiser R.

Cancer Res. 2024; doi.org/10.1158/0008-5472.CAN-23-3553

Differential prolyl hydroxylation by six Physcomitrella prolyl-4 hydroxylases

Christine Rempfer a,b,1, Sebastian N.W. Hoernstein a,2, Nico van Gessel a,3, Andreas W. Graf a,4, Roxane P. Spiegelhalder a,5,6, Anne Bertolini a,7, Lennard L. Bohlender a,8, Juliana Parsons a,9, Eva L. Decker a,10, Ralf Reski a,b,c,*,11

Differential prolyl hydroxylation by six Physcomitrella prolyl-4 hydroxylases

Christine Rempfer a,b,1, Sebastian N.W. Hoernstein a,2, Nico van Gessel a,3, Andreas W. Graf a,4, Roxane P. Spiegelhalder a,5,6, Anne Bertolini a,7, Lennard L. Bohlender a,8, Juliana Parsons a,9, Eva L. Decker a,10, Ralf Reski a,b,c,*,11

Science Direct; doi.org/10.1016/j.csbj.2024.06.014

Anti-PD-1 cancer immunotherapy induces central nervous system immune-related adverse events by microglia activation

Vinnakota JM, Adams RC, Athanassopoulos D, Schmidt D, Biavasco F, Zähringer A, Erny D, Schwabenland M, Langenbach M, Wenger V, Salié H, Cook J, Mossad O, Andrieux G, Dersch R, Rauer S, Duquesne S, Monaco G, Wolf P, Blank T, Häne P, Greter M, Becher B, Henneke P, Pfeifer D, Blazar BR, Duyster J, Boerries M, Köhler N, Chhatbar CM, Bengsch B, Prinz M, Zeiser R.

Sci Transl Med. 2024; doi: 10.1126/scitranslmed.adj9672.

Development of combination therapies with BTK inhibitors and dasatinib to treat CNS-infiltrating E2A-PBX1+/preBCR+ ALL.

Gentile G, Poggio T, Catalano A, Voutilainen M, Lahnalampi M, Andrade-Martinez M, Ma T, Sankowski R, Goncharenko L, Tholen S, Han K, Morgens DW, Prinz M, Lübbert M, Engel S, Hartmann TN, Cario G, Schrappe M, Lenk L, Stanulla M, Duyster J, Bronsert P, Bassik MC, Cleary ML, Schilling O, Heinäniemi M, Duque-Afonso J.

Blood Adv. 2024; doi: 10.1182/bloodadvances.2023011582.