CIBSS - Centre for integrative Biological Signalling Studies CIBSS

Correlations Within and Between Highly Multiplexed Proteomic Assays of Human Plasma

Rooney MR, Chen J, Ballantyne CM, Hoogeveen RC, Boerwinkle E, Yu B, Walker KA, Schlosser P, Selvin E, Chatterjee N, Couper D, Grams ME, Coresh J.

Clin Chem. 2025; doi: 10.1093/clinchem/hvaf030. Online ahead of print.

The number of assays on proteomic platforms has grown rapidly. Comparisons of precision on the latest platforms—SomaScan 11k and Olink Explore HT—have not yet been established. Cross-platform agreement was assessed for overlapping proteins of CV and Spearman correlations.