CIBSS - Centre for integrative Biological Signalling Studies CIBSS

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CIBSS Publications

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Beyond genotype: challenges in predicting disease risk for carriers of biallelic perforin variants

Wegehaupt O, Borisov O, Sieni E, Oyen F, Mann J, Coniglio ML, Chinnici A PhD, Pegoraro F, Beneforti L, Gilmour KC, Moshous D, de Saint Basile G, Zhang W, Marsh RA, De Fusco C, Wustrau K, Timeus F, Micalizzi C, Gunsilius E, Hosking L, Choo S, Ghosh S, Köttgen A, Lehmberg K, Ehl S.

Blood. 2025 Mar 16; doi: 10.1182/blood.2024027954. Online ahead of print.

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Uncovering risk factors of premature mortality in Common Variable Immunodeficiency (CVID)

Bez P, Smits B, Geier C, Hirsch A, Caballero de Oyteza A, Proietti M, Grimbacher B, Wolkewitz M, Goldacker S, Warnatz K.

J Allergy Clin Immunol Pract. 2025; doi: 10.1016/j.jaip.2025.03.009.

A transcriptional atlas of gut-innervating neurons reveals activation of interferon signaling and ferroptosis during intestinal inflammation

Forster PM, Jakob MO, Yusuf D, Bubeck M, Limberger H, Luo Y, Thieme P, Polici A, Sterczyk N, Boulekou S, Bartel L, Cosovanu C, Witkowski M, González-Acera M, Kühl AA, Weidinger C; TRR241 IBDome Consortium; Backofen R, Hegazy AN, Patankar JV, Klose CSN.

Neuron. 2025; doi: 10.1016/j.neuron.2025.02.018. Online ahead of print.

Infusing structural assumptions into dimensionality reduction for single-cell RNA sequencing data to identify small gene sets

Hackenberg M, Brunn N, Vogel T, Binder H.

Commun Biol. 2025; doi: 10.1038/s42003-025-07872-9.

Mucociliary cell type compositions - bridging the gap between genes and emergent tissue functions

Waltentek P

Cells Dev. 2025; doi: 10.1016/j.cdev.2025.204019. Online ahead of print.

Lectin-Based Substrate Detection in Fabry Disease Using the Gb3-Binding Lectins StxB and LecA.

Elçin-Guinot S, Lagies S, Avi-Guy Y, Neugebauer D, Huber TB, Schell C, Kammerer B, Römer W.

Int J Mol Sci. 2025; doi: 10.3390/ijms26052272.

 

 

Fight to survive: Marchantia synthesizes newly identified metabolites in response to wounding

Pitsili E, Maric A.

Plant Physiol. 2025 Mar 4. doi: 10.1093/plphys/kiaf066. Online ahead of print.

Structural basis of ClC-3 inhibition by TMEM9 and PI(3,5)P2

Schrecker M, Son Y, Planells-Cases R, Kar S, Vorobeva V, Schulte U, Fakler B, Jentsch TJ, Hite RK.

bioRxiv [Preprint]. 2025; doi: 10.1101/2025.02.28.640562.

Comparative analysis using a chromosome-scale genome assembly for Funaria hygrometrica suggests greater collinearity in mosses than in seed plants

Kirbis A, Rahmatpour N, Dong S, Yu J, Waser L, Huang H, van Gessel N, Waller M, Reski R, Lang D, Rensing S A, Temsch Eva M, Wegrzyn J L, Goffinet B, Liu Y, Szövényi P.

Commun Biol. 2025; doi: 10.1038/s42003-025-07749-x.

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Epigenetic control of cell identities from epiblast to gastrulation

Schüle K M, Probst S.

FEBS J. 2025 Feb 22. doi: 10.1111/febs.70024. Online ahead of print.

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