CIBSS Launchpad Funds Recipients 2022

Dr. Philipp Schwenk

Postdoc

Dr. Philipp Schwenk

Contact

Dr. Philipp Schwenk
Department of Molecular Plant Physiology, Faculty of Biology,
University of Freiburg

T +49 761 203 67868
philipp.schwenk(at)biologie.uni-freiburg.de

Further Information

Selected publications:

  • Phytochrome A mediates the disassembly of processing bodies in far-red light.
    Schwenk P, Hiltbrunner A.
    Front Plant Sci. 2022 Feb 23;13:828529.
  • Uncovering a novel function of the CCR4-NOT complex in phytochrome A-mediated light signalling in plants.
    Schwenk P, Sheerin DJ, Ponnu J, Staudt AM, Lesch KL, Lichtenberg E, Medzihradszky KF, Hoecker U, Klement E, Viczián A, Hiltbrunner A.
    Elife. 2021 Mar 30;10:e63697.
  • COLD REGULATED 27 and 28 are targets of CONSTITUTIVELY PHOTOMORPHOGENIC 1 and negatively affect phytochrome B signalling.
    Kahle N, Sheerin DJ, Fischbach P, Koch LA, Schwenk P, Lambert D, Rodriguez R, Kerner K, Hoecker U, Zurbriggen MD, Hiltbrunner A.
    Plant J. 2020 Nov;104(4):1038-1053.
  • PCH1 and PCHL promote photomorphogenesis in plants by controlling phytochrome B dark reversion.
    Enderle B, Sheerin DJ, Paik I, Kathare PK, Schwenk P, Klose C, Ulbrich MH, Huq E, Hiltbrunner A.
    Nat Commun. 2017 Dec 20;8(1):2221.

The Light Reactivity of Liquid-liquid Phase Separated Organelles in Arabidopsis thaliana

Liquid-liquid phase separation (LLPS) is a process in which two liquids unmix, comparable from the unmixing of vinegar and oil in a salad dressing. In recent years, this process of separating different cellular components into non-membranous organelles have gained attention as a mean of compartmentalization of reaction spaces. In plants, ambient light is detected and integrated by several classes of receptors, with phytochromes being one of the most important ones. Phytochromes are involved in several LLPS-related processes, such as the formation of subnuclear bodies, so-called photobodies but also cytoplasmic structures, termed SAPs. This and other similar structures are known for 20 years, but their contents and function remain partially elusive to date. In this project, I want to biochemically purify phytochrome-related LLPS-formed structures, and subject them to a transcriptomic and proteomic analysis. This will help to understand the mechanisms behind the light reactivity of LLPS in plants and its consequences for the adaption to the changing environmental conditions a plant is exposed to.sequences for the adaption to the changing environmental conditions a plant is exposed to.