Ten selected publications
COX17 Acetylation via MOF-KANSL Complex Promotes Mitochondrial Function and Integrity
Guhathakurta, S., Erdogdu, N.U., Hoffmann, J.J., Grzadzielewska, I., Schendzielorz, A., Martensson, C.U., Corrado, M., Karoutas, A., Seyfferth, J., Warscheid, B., Pfanner, N., Becker, T., & Akhtar, A.
Nature Metabolism (2023). Featured in News & Views by Natalie Niemi (Nat. Met.) and by Dimitris Typas (Nature Structural and Molecular Biology).
Neural Metabolic Imbalance Induced by MOF Dysfunction Triggers Pericyte Activation and Breakdown of Vasculature
Sheikh, B. N., Guhathakurta, S., Tsang, T.H., Schwabenland, M., Renschler, G. V., Herquel, B., Bhardwaj, V., Holz, H., Stehle, T., Bondareva, O., Aizarani, N., Mossad, O., Kretz, O., Reichardt, W., Chatterjee, A., Braun, L., Thevenon, J., Sartelet, H., Blank, T., Grün, D., Elverfeldt, D., Huber, T.B., Vestweber, D., Avilov, S., Prinz, M., Buescher, J.M., & Akhtar, A.
Nature Cell Biology 22, pp. 828–841 (2020).
The NSL Complex Maintains Nuclear Architecture Stability via Lamin A/C Acetylation
Karoutas, A., Szymanski, W., Rausch, T., Guhathakurta, S., Rog-Zielinska, E.A., Pyronnet, R., Seyfferth, J., Chen, H.R., Leeuw, R., Herquel, B., Kimura, H., Mittler, G., Kohl, P., Medalia, O., Korbel, J.O., & Akhtar, A.
Nature Cell Biology 21, pp. 1248–1260 (2019). Featured in News & Views by Varvara V. Papova & Jerry L. Workman.
Systematic Identification of Cell-Cell Communication Networks in the Developing Brain
Sheikh, B. N., Bondareva, O., Guhathakurta, S., Tsang, T.H., Sikora, K., Aizarani, N., Sagar, Holz, H., Grün, D., Hein, L., & Akhtar, A.
iScience 21, pp. 273–287 (2019).
The Non-Specific Lethal (NSL) Complex at the Crossroads of Transcriptional Control and Cellular Homeostasis
Sheikh, B. N., Guhathakurta, S., & Akhtar, A. (Equal contribution)
EMBO Reports 20, p. e47630 (2019).