Associate Investigators

Prof. Dr. Björn Lillemeier

Prof. Dr. Björn Lillemeier


Prof. Dr. Björn Lillemeier
Institute of Biology III – Molecular Immunology (Faculty of Biology)
University of Freiburg


Further Information


10 selected publications

  • Engineering of cells that display phytochrome B on their surface for optogenetic studies of cell-cell interactions.
    Russ M, Ehret AK, Hörner M, Peschkov D, Bohnert R, Idstein V, Minguet S, Weber W, Lillemeier BF, Yousefi OS, Schamel WW. (2023).
    Opto-APC: Front Mol Biosci. Feb 20;10:1143274.
  • Chaotropic Perturbation of Noncovalent Interactions of the Hemagglutinin Tag Monoclonal Antibody Fragment Enables Superresolution Molecular Census.
    Gunasekara H, Munaweera R, Novotná L, Lillemeier BF, Hu YS (2022).
    ACS Nano. Dec 27;16(12):21645.
  • Septins organize endoplasmic reticulum-plasma membrane junctions for STIM1-ORAI1 calcium signalling.
    Katz ZB, Zhang C, Quintana A, Lillemeier BF, Hogan PG (2019).
    Sci Rep. 9(1):10839.
  • Phosphotyrosine-dependent interaction between the kinases PKCθ and Zap70 promotes proximal TCR signaling.
    Xie J, Han X, Zhao C, Canonigo-Balancio AJ, Yates JR 3rd, Li Y, Lillemeier BF, Altman A (2019).
    Sci Signal. 12(577):eaar3349.
  • A cycle of Zap70 kinase activation and release from the TCR amplifies and disperses antigenic stimuli.
    Katz ZB, Novotná L, Blount A, Lillemeier BF (2017).
    Nat Immunol. 18(1):86-95.
  • Superresolution imaging reveals nanometer- and micrometer-scale spatial distributions of T-cell receptors in lymph nodes.
    Hu YS, Cang H, Lillemeier BF (2016).
    Proc Natl Acad Sci U S A. 113(26):7201-6.
  • B cell antigen receptors of the IgM and IgD classes are clustered in different protein islands that are altered during B cell activation.
    Maity PC, Blount A, Jumaa H, Ronneberger O, Lillemeier BF, Reth M (2015).
    Sci Signal. 8(394):ra93.
  • T cell receptor dwell times control the kinase activity of Zap70.
    Klammt C, Novotná L, Li DT, Wolf M, Blount A, Zhang K, Fitchett JR, Lillemeier BF (2015). Nat Immunol. 16(9):961-9.
  • How membrane structures control T cell signaling.
    Klammt C, Lillemeier BF (2012).
    Front Immunol. 3:291.
  • TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation.
    Lillemeier BF, Mörtelmaier MA, Forstner MB, Huppa JB, Groves JT, Davis MM (2010).
    Nat Immunol. 11(1):90-6.