Our group aims at understanding how the molecular machinery of autophagy, the cellular waste disposal system, works.
The major focus of our work lays on dissecting the molecular mechanisms in autophagy. The field of autophagy is still very young, as it only emerged in the last two decades. Many basic questions remain unanswered, such as how autophagosomes form and where the autophagic membranes come from. We believe in hypothesis driven basic research to study how cells function. Our vision is to first study the basic molecular mechanisms in a simple setup, to then understand how a pathway acts in more complex situations, such as multicellular organisms or diseases.