CIBSS - Centre for integrative Biological Signalling Studies CIBSS

Mapping the origin and fate of myeloid cells in distinct compartments of the eye by single-cell profiling

Wieghofer P, Hagemeyer N, Sankowski R, Schlecht A, Staszewski O, Amann L, Gruber M, Koch J, Hausmann A, Zhang P, Boneva S, Masuda T, Hilgendorf I, Goldmann T, Böttcher C, Priller J, Rossi FM, Lange C, Prinz M.

EMBO J. 2021; doi: 10.15252/embj.2020105123

Our results highlight the heterogeneity of myeloid subsets and their dynamics in the eye that provide new insights into the innate immune system in this organ which may offer new therapeutic targets for ophthalmological diseases.