Deciphering the molecular logic of WOX5 function in the root stem cell organizer

Zhang N, Bitterli P, Oluoch P, Hermann M, Aichinger E, Groot EP, Laux T.

EMBO J. 2025; doi: 10.1038/s44318-024-00302-2

We unveil the transcriptional and epigenetic landscapes in the Arabidopsis root stem cell organizer and the role of WOX5 within them. We uncover unexpected WOX5-regulated pathways, suggesting a role for organizer cells as reserve stem cells and primed cells for prospective progenitor fates.