Dynamic evolution of TCF3-PBX1 leukemias at the single-cell level under chemotherapy pressure

Kusterer M, Lahnalampi M, Voutilainen, Brand A, Pennisi S, Norona J, Gentile G, Herzog H, Greve G, Lübbert M, Sipola M, Kaartinen E, Sankowski R, Prinz M, Killmer S, Lago M S, Bengsch B, Cysar S R, Aumann K, Werner M, Duyster J, Lohi O, Heinäniemi M, Duque-Afonso J.

Hemasphere. 2025; doi: 10.1002/hem3.70071.

Transcriptomics and phospho‐proteomics revealed distinct pathways that may underlie chemotherapy resistance and might be suitable for pharmacological interventions in human ALL.