Expanding the Inositol Pyrophosphate Toolbox: Stereoselective Synthesis and Application of PP-InsP4 Isomers in Plant Signaling

Ritter K, Braun AS, Liu G, Lu M, Gaugler V, Schaaf G, Jessen HJ.

Angew Chem Int Ed Engl. 2025; doi: 10.1002/anie.202507058. 

A unifying synthesis of inositol pyrophosphates with free OH groups is developed and applied in the analysis of plant phosphate signalling.