Inositol pyrophosphate InsP8 acts as an intracellular phosphate signal in arabidopsis

Dong J, Ma G, Sui L, Wei M, Satheesh V, Zhang R, Ge S, Li J, Zhang TE, Wittwer C, Jessen HJ, Zhang H, An GY, Chao DY, Liu D, Lei M.

Mol Plant. 2019;12(11):1463-1473.

Mol Plant.           online article

We demonstrate that the inositol pyrophosphate InsP8 directly binds to the SPX domain of SPX1 protein, a phosphate sensor in plants. This study therefore unveils that InsP8 regulates phosphate homeostasis in plants.