CIBSS - Centre for integrative Biological Signalling Studies CIBSS

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CIBSS Publications

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Pumilio differentially binds to mRNA 3' UTR isoforms to regulate localization of synaptic proteins

Grzejda D, Hess A, Rezansoff A, Gorey S, Carrasco J, Alfonso-Gonzalez C, Tsagkris S, Neuhaus L, Shi M, Ozbulut H C, Vögtle F-N, Vlachos A, Hilgers V.

EMBO Rep. 2025 Feb 21. doi: 10.1038/s44319-025-00401-z. Online ahead of print.

Metabolite-Responsive Control of Transcription by Phase Separation-Based Synthetic Organelles

Jerez-Longres C, Weber W.

ACS Synth Biol. 2025 Feb 15. doi: 10.1021/acssynbio.4c00633. Online ahead of print.

Anti-myeloperoxidase IgM B cells in anti-neutrophil cytoplasmic antibody-associated vasculitis

Wortel C M, van de Wetering R, Stork E M, Kissel T, Reijm S, van der Woude D, van Schie K A, Trouw L A, Teng Y, Rutgers A, Heeringa P, Voll R E , Rizzi M, Venhoff N, Toes R, Scherer H U.

Nat Commun. 2025 Feb 12. doi: 10.1038/s41467-025-56786-x.

The intestinal microbiome and metabolome discern disease severity in cytotoxic T-lymphocyte-associated protein 4 deficiency

Chandrasekaran P, Krausz M, Han Y, Mitsuiki N, Gabrysch A, Nöltner C, Proietti M, Heller T, Grou C, Calderon V, Subramanian P, Jones D R, Siu Y, Deming C, Conlan S, Holland S M, Segre J A, Uzel G, Grimbacher B, Falcone E L.

Microbiome. 2025 Feb 11. doi: 10.1186/s40168-025-02028-7.

Adiponectin reduces immune checkpoint inhibitor-induced inflammation without blocking anti-tumor immunity

Braun L M, Giesler S, Andrieux G, Riemer R, Talvard-Balland N, Duquesne S, Rückert T, Unger S, Kreutmair S, Zwick M, Follo M, Hartmann A, Osswald N, Melchinger W, Chapman S, Hutchinson J A, Haferkamp S, Torster L, Kött J, Gebhardt C, Hellwig D, Karantzelis N, Wallrabenstein T, Lowinus T, Yücel M, Brehm N, Rawluk J, Pfeifer D, Bronsert P, Rogg M, Mattern S, Heikenwälder M, Fusco S, Malek N P, Singer S, Schmitt-Graeff A, Ceteci F, Greten F R, Blazar B R, Boerries M, Köhler N, Duyster J, Ihorst G, Lassmann S, Keye P, Minguet S, Schadendorf D, Ugurel S, Rafei-Shamsabadi D, Thimme R, Hasselblatt P, Bengsch B, Schell C, Pearce E L, Meiss F, Becher B, Funke-Lorenz C, Placke J-M, Apostolova P, Zeiser R.

Cancer Cell. 2025 Feb 10. doi: 10.1016/j.ccell.2025.01.004.

Signaling Activation and Modulation in Extrafollicular B Cell Responses

Staniek J, Rizzi M.

Immunol Rev. 2025 Mar. doi: 10.1111/imr.70004.

Biochemical and biophysical characterization of inositol-tetrakisphosphate 1-kinase inhibitors

Ng MY, Wang H, Zhang H, Prucker I, Perera L, Goncharova E, Wamiru A, Jessen HJ, Stanley RE, Shears SB, Luo J, O'Keefe BR, Wilson BAP.

J Biol Chem. 2025; doi: 10.1016/j.jbc.2025.108274.

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ESIPT fluorescence turn-on sensors for detection of short chain inorganic polyphosphate in water

Roy SK, Moser S, Dürr-Mayer T, Hinkelmann R, Jessen HJ.

Org Biomol Chem. 2025, doi: 10.1039/d4ob01926a.

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Dynamic evolution of TCF3-PBX1 leukemias at the single-cell level under chemotherapy pressure

Kusterer M, Lahnalampi M, Voutilainen, Brand A, Pennisi S, Norona J, Gentile G, Herzog H, Greve G, Lübbert M, Sipola M, Kaartinen E, Sankowski R, Prinz M, Killmer S, Lago M S, Bengsch B, Cysar S R, Aumann K, Werner M, Duyster J, Lohi O, Heinäniemi M, Duque-Afonso J.

Hemasphere. 2025; doi: 10.1002/hem3.70071.

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IDH-mutant astrocytomas with primitive neuronal component have a distinct methylation profile and a higher risk of leptomeningeal spread

Hinz F, Friedel D, Korshunov A, Ippen F M, Bogumil H, Banan R, Brandner S, Hasselblatt M, Boldt H B, Dirse V, Dohmen H, Aronica E, Brodhun M, Broekman M L D, Capper D, Cherkezov A, Deng M Y, van Dis V, Felsberg J, Frank S, French PJ, Gerlach R, Göbel K, Goold E, Hench J, Kantelhardt S, Kohlhof-Meinecke P, Krieg S, Mawrin C, Morrison G, Mühlebner A, Ozduman K, Pfister S M, Poliani P L, Prinz M, Reifenberger G, Riemenschneider M J, Sankowski R, Schrimpf D, Sill M, Snuderl M, Verdijk R M, Voisin M R, Wesseling P, Wick W, Reuss D E, von Deimling A, Sahm F, Maas S L N, Suwala A K.

Acta Neuropathol. 2025; doi: 10.1007/s00401-025-02849-8.

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