CIBSS - Centre for integrative Biological Signalling StudiesCIBSS

Associate Investigators

Dr. Claudia Jessen-Trefzer

Dr. Claudia Jessen-Trefzer

Contact

Dr. Claudia Jessen-Trefzer
Department of Pharmaceutical Biology and Biotechnology
(Faculty of Chemistry and Pharmacy)
University of Freiburg

T +49 761 203 6074
claudia.jessen-trefzer(at)pharmazie.uni-freiburg.de

Further Information

10 selected publications:

  • Artificial Metalloenzymes in a Nutshell: The Quartet for Efficient Catalysis
    Ebensperger P*, Jessen-Trefzer C* (2021)
    Biol Chem - De Gruyter, online ahead of print. doi.org/10.1515/hsz-2021-0329.
  • Inside a Shell-Organometallic Catalysis Inside Encapsulin Nanoreactors.
    Lohner P, Zmyslia M, Thurn J, Pape JK, Gerasimaitė R, Keller-Findeisen J, Groeer S, Deuringer B, Süss R, Walther A, Hell SW, Lukinavičius G, Hugel T, Jessen-Trefzer C (2021).
    Angew Chem Int Ed Engl. 60(44):23835-23841
  • Pyridinium Modified Anthracenes and Their Endoperoxides Provide a Tunable Scaffold with Activity against Gram-Positive and Gram-Negative Bacteria.
    Wang X, Bittner T, Milanov M, Kaul L, Mundinger S, Koch HG, Jessen-Trefzer C, Jessen HJ (2021).
    ACS Infect Dis. 7(8):2073-2080.
  • The Two-Component Locus MSMEG_0244/0246 Together With MSMEG_0243 Affects Biofilm Assembly in M. smegmatis Correlating With Changes in Phosphatidylinositol Mannosides Acylation.
    Li M, Gašparovič H, Weng X, Chen S, Korduláková J*, Jessen-Trefzer C*.
    Front Microbiol. 2020 Sep 11;11:570606
    *corresponding author
  • Understanding the Mechanism of Action of Pyrrolo[3,2-b]quinoxaline-derivatives as Kinase Inhibitors.
    Unzue A, Jessen-Trefzer C, Spiliotopoulos D, Gaudio E, Tarantelli C, Dong J, Zhao H, Leibl J, Zahler S, Bernasconi E, Sartori G, Cascione L, Bertoni F, Sledz P, Caflisch A, Nevado C (2021) RSC Medicinal Chemistry 11, 665-675.
  • Four phosphates at one blow: access to pentaphosphorylated magic spot nucleotides and their analysis by capillary electrophoresis.
    Haas TM, Qiu D, Häner M, Angebauer L, Ripp A, Singh J, Koch HG, Jessen-Trefzer C, Jessen HJ (2020)
    J Org Chem 85(22):14496-14506
  • Detection and Characterization of a Mycobacterial L-Arabinofuranose ABC Transporter Identified with a Rapid Lipoproteomics Protocol.
    Li M, Müller C, Fröhlich K, Gorka O, Zhang L, Groß O, Schilling O, Einsle O, Jessen-Trefzer C.
    Cell Chem Biol. 26(6):852-862
  • Trehalose Conjugation Enhances Toxicity of Photosensitizers against Mycobacteria.
    Dutta AK, Choudhary E, Wang X, Záhorszka M, Forbak M, Lohner P, Jessen HJ, Agarwal N, Korduláková J, Jessen-Trefzer C* (2019).
    ACS Cent Sci. 2019 Apr 24;5(4):644-650
    *corresponding author
  • Benzothiazinones are suicide inhibitors of mycobacterial decaprenylphosphoryl-β-D-ribofuranose 2'-oxidase DprE1.
    Trefzer C, Škovierová H, Buroni S, Bobovská A, Nenci S, Molteni E, Pojer F, Pasca MR, Makarov V, Cole ST, Riccardi G, Mikušová K, Johnsson K.
    J Am Chem Soc. 134(2):912-5
  • Benzothiazinones: prodrugs that covalently modify the decaprenylphosphoryl-β-D-ribose 2'-epimerase DprE1 of Mycobacterium tuberculosis.
    Trefzer C, Rengifo-Gonzalez M, Hinner MJ, Schneider P, Makarov V, Cole ST, Johnsson K (2010).
    J Am Chem Soc. 132(39):13663-5.