CIBSS - Centre for integrative Biological Signalling Studies CIBSS

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CIBSS Publications

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Opposing roles of pseudokinases NRBP1 and NRBP2 in regulating L1 retrotransposition

Yang W, Cong S, Li R, Schwarz J, Schulze T, Gevelhoff RA, Chen X, Ullrich S, Falkenstein K, Ott D, Eixmann P, Trentino A, Thien A, Heidmann T, Schulze E, Warscheid B, Baumeister R, Qi W.

Nat Commun. 2025; doi: 10.1038/s41467-025-61626-z.

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Synthesis of monodisperse inorganic polyphosphate polyP10 via a photocaging strategy

Moser S, Hans G, Ma J, Haas T, Jork N, Bauer F, Breit B, Jessen HJ.

Chem Sci. 2025; doi: 10.1039/d5sc04037j. Online ahead of print.

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A multiomic resource to interpret genetic associations with kidney function

Schlosser P, Köttgen A

Kidney Int. 2025; doi: 10.1016/j.kint.2025.04.028.

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Molecular machineries and pathways of mitochondrial protein transport

Endo T, Wiedemann N.

Nat Rev Mol Cell Biol. 2025; doi: 10.1038/s41580-025-00865-w.

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Expanding the Inositol Pyrophosphate Toolbox: Stereoselective Synthesis and Application of PP-InsP4 Isomers in Plant Signaling

Ritter K, Braun AS, Liu G, Lu M, Gaugler V, Schaaf G, Jessen HJ.

Angew Chem Int Ed Engl. 2025 Jul 1:e202507058. doi: 10.1002/anie.202507058. Online ahead of print.

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Circulating Proteins for Prediction of Kidney Disease Progression and Cardiovascular Outcomes: Individual Participant Data Meta-Analysis of Four Cohorts

Lopez-Silva C, Surapaneni A, Coresh J, Chen TK, Schlosser P, Rhee EP, Waikar SS, Schmidt IM, Deo R, Ganz P, Dubin R, Ramachandran VS, Kimmel PL, Schrauben S, Parikh CR, Bonventre JV, Dobre M, Rao PS, Ricardo AC, Weir MR, Grams ME; CRIC Study Investigators.

Am J Nephrol. 2025; doi: 10.1159/000547138. Online ahead of print.

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AhR activation mitigates graft-versus-host disease of the central nervous system by reducing microglial NF-κB signaling

Zähringer A, Morgado I, Erny D, Ingelfinger F, Gawron J, Chatterjee S, Wenger V, Schmidt D, Schwöbel L, Adams RC, Langenbach M, Hartmann A, Osswald N, Wolf J, Schlunck G, Briquez PS, Grueter K, Ruess DA, Frew I, Burk AC, Holzmüller V, Grimbacher B, Michonneau D, Andrieux G, Socié G, Kolter J, Boerries M, Follo M, Blaeschke F, Sevenich L, Prinz M, Zeiser R, Vinnakota JM.

Blood Adv. 2025; doi: 10.1182/bloodadvances.2024015000.

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Stereoselective chemoenzymatic phytate transformations provide access to diverse inositol phosphate derivatives

Häner GM, Liu G, Lange E, Jork N, Ditrich K, Greiner R, Schaaf G, Jessen HJ

Chem Sci. 2025; doi: 10.1039/d5sc02844b.

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MCAM is a prognostic biomarker in patients with liver cirrhosis and HCC

Stockinger E, Luxenburger H, Bettinger D, Berlin C, Obwegs D, Sagar, Sturm L, Gromak M, Gairing S J, Foerster F, Labenz C, MacNelly S, Boettler T, Holzner P, Bronsert P, Bengsch B, Thimme R, Hofmann M, Roehlen N.

Hepatol Commun. 2024 Oct 3. doi: 10.1097/HC9.0000000000000532. eCollection 2024 Oct 1.

Beyond genotype: challenges in predicting disease risk for carriers of biallelic perforin variants

Wegehaupt O, Borisov O, Sieni E, Oyen F, Mann J, Coniglio ML, Chinnici A PhD, Pegoraro F, Beneforti L, Gilmour KC, Moshous D, de Saint Basile G, Zhang W, Marsh RA, De Fusco C, Wustrau K, Timeus F, Micalizzi C, Gunsilius E, Hosking L, Choo S, Ghosh S, Köttgen A, Lehmberg K, Ehl S.

Blood. 2025; doi: 10.1182/blood.2024027954.

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