CIBSS - Centre for integrative Biological Signalling Studies CIBSS

PUBLICATIONS

CIBSS Publications

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Mitochondrial KMT9 methylates DLAT to control pyruvate dehydrogenase activity and prostate cancer growth

Jia Y, Wang S, Urban S, Müller J M, Sum M, Wang Q, Bauer H, Schulte U, Rampelt H, Pfanner N, Schüle K M, Imhof A, Forné I, Berlin C, Sigle A, Gratzke C, Greschik H, Metzger E, Schüle R.

Nat Commun. 2025 Jan 30. doi: 10.1038/s41467-025-56492-8.

Stalled disomes marked by Hel2-dependent ubiquitin chains undergo Ubp2/Ubp3-mediated deubiquitination upon translational run-off

Scazzari M, Zhang Y, Moddemann A, Rospert S.

Commun Biol. 2025 Jan 28. doi: 10.1038/s42003-025-07569-z.

A Noncatalytic Cysteine Residue Modulates Cobalamin Reactivity in the Human B12 Processing Enzyme CblC

Esser AJ, Sastre S, Dinh TJ, Tanner V, Wingert V, Klotz K, Jacobsen DW, Spiekerkoetter U, Schilling O, Zeida A, Radi R, Hannibal L.

Biochemistry. 2025; doi: 10.1021/acs.biochem.4c00613

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Characterizing the omics landscape based on 10,000+ datasets

Brombacher E, Schilling O, Kreutz C.

Sci Rep. 2025 Jan 25. doi: 10.1038/s41598-025-87256-5.

Differential GTP-dependent in-vitro polymerization of recombinant Physcomitrella FtsZ proteins

Milferstaedt S W L, Joest M, Bohlender L L, Hoernstein S N W, Özdemir B, Decker E L, van der Does C, Reski R.

Sci Rep. 2025 Jan 24; doi: 10.1038/s41598-024-85077-6.

Structural Insights into Broad-Range Polyphosphate Kinase 2-II Enzymes Applicable for Pyrimidine Nucleoside Diphosphate Synthesis

Kuge M, Keppler M, Friedrich F, Saleem-Batcha R, Winter J, Prucker I, Germer P, Gerhardt S, Einsle O, Jung M, Jessen H J, Andexer J.

Chembiochem. 2025 Feb 3; doi: 10.1002/cbic.202400970. Epub 2025 Feb 4.

Mitochondrial protein import stress

Pfanner N, den Brave F, Becker T.

Nat Cell Biol. 2025; doi: 10.1038/s41556-024-01590-w.

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Phase separation of initiation hubs on cargo is a trigger switch for selective autophagy

Licheva M, Pflaum J, Babic R, Manchilla H, Elsässer J, Boyle M, Hollenstein DM, Jimenez-Niebla J, Pleyer J, Heinrich M, Wieland FG, Brenneisen J, Eickhorst C, Brenner J, Jiang S, Hartl M, Welsch S, Hunte C, Timmer J, Wilfling F, Kraft C

Nat Cell Biology 2025; DOI: https://doi.org/10.1038/s41556-024-01572-y

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Integration of basal and apical embryo lineage regulators controls F-actin cable integrity and zygote asymmetry in Arabidopsis

Xiong F, Zhang Z, Gong W, Hermann M, Bak D T, Garbsch F, Laux T.

Proc Natl Acad Sci USA. 2025 Jan 7. doi: 10.1073/pnas.2402720122. Epub 2024 Dec 30.

The effect of HLA genotype on disease onset and severity in CTLA-4 insufficiency

Posada-Cantera S, Mitsuiki N, Emmerich F, Patiño V, Lorenz H-M, Neth O, Dybedal I, Taskén K, Schäffer A A, Grimbacher B, Gámez-Díaz L.

Front Immunol. 2025 Jan 6. doi: 10.3389/fimmu.2024.1447995. eCollection 2024.

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