CIBSS - Centre for integrative Biological Signalling Studies CIBSS

PUBLICATIONS

CIBSS Publications

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Early microglia progenitors colonize the embryonic CNS via integrin-mediated migration from the pial surface

Petry P, Oschwald A, Merkt S, Dinh TJ, Andrieux G, Crisand C, Botterer H, Nent E, Paterson N, Havermans M, Sankowski R, Schilling O, Boerries M, Amann L, Groß O, Schlitzer A, Prinz M, Lämmermann T, Kierdorf K.

Dev Cell. 2026; doi: 10.1016/j.devcel.2025.08.012

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Single-cell multiome and spatial profiling reveals pancreas cell type-specific gene regulatory programs of type 1 diabetes progression

Melton R, Jimenez S, Elison W, Tucciarone L, Howell A, Wang G, Berti D, Beebe E, Miller M, Zeng C, McGrail C, VanderStel K, Korgaonkar K, Elgamal R, Mummey H, Chiou J, Griffin E, Kusmartseva I, Atkinson M, Preissl S, Theis FJ, Sander M, Gaulton KJ.

Sci Adv. 2025; doi: 10.1126/sciadv.ady0080.

Cyclin-dependent kinase inhibitor 1A mediates mouse line- and fate-dependent cellular responses in Cx3cr1-Cre genetic tools

Yamasaki A, Shintaku H, Harada A, Maehara K, Tanaka K, Saeki M, Ito M, Konishi H, Tsuda M, Prinz M, Kishi Y, Ohkawa Y, Yamamoto S, Masuda T.

Cell Rep. 2025; doi: 10.1016/j.celrep.2025.116267.

Enhanced ISGylation via USP18 Isopeptidase Inactivation Fails to Mitigate the Inflammatory or Functional Course of Coxsackievirus B3-Induced Myocarditis

Kelm N, Kespohl M, Borowski S, Ochs S, Knobeloch KP, Huis In 't Veld LGM, Klingel K, Beling A.

Cell Physiol Biochem. 2025; doi: 10.33594/000000811.

Sensory neurons shape local macrophage identity via TGF-β signaling

Kolter J, Döring CL, Sarout S, Baasch S, Steele L, Alsumati R, Lucena Silva GV, Aníbal Silva CE, Paiva IM, Mansoori Moghadam Z, Gres V, Lohrmann F, Aktories P, Buchegger T, Bijnen M, Doumard L, Voisin B, Le Foll C, Lachmann N, Greter M, Kierdorf K, Haniffa M, Cunha TM, Flacher V, Henneke P.

Immunity. 2025; doi: 10.1016/j.immuni.2025.08.004

Synthetic trap-peptides identify a TOM complex phosphatase - PP2A dephosphorylates Tom6

Scheinost L, Ludwig C, Höfflin N, Taskin AA, Marada A, Vögtle FN, Meisinger C, Köhn M.

FEBS J. 2025; doi: 10.1111/febs.70246. Online ahead of print.

Functional conservation and divergence of the WOX gene family in regulating meristem activity: From Arabidopsis to crops

Du F, Chang Z, Kong X, Xia L, Zhou W, Laux T, Zhang L.

Plant Physiol. 2025; doi: 10.1093/plphys/kiaf374.

Stretch-Induced Increase in Ca2+-Spark Rate in Rabbit Atrial Cardiomyocytes Requires TRPA1 and Intact Microtubule Network

Fu J, Cameron BA, Schönleitner P, Schiatti T, Kuiper M, Kittel AS, Simon-Chica A, Madl J, Kreutz C, Filgueiras-Rama D, Schotten U, Römer W, Ravens U, Kohl P, Rog-Zielinska EA, Antoons G, Peyronnet R.

J Am Heart Assoc. 2025; doi: 10.1161/JAHA.124.040495

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STAT3 haploinsufficiency is associated with autosomal dominant hyper-IgE syndrome

Andreani V, Forde AJ, Fliegauf M, Bressan G, Noé V, Ott N, Saghafi S, Vornholz L, Isay SE, Ruland J, Henneke P, Grimbacher B.

Sci Adv. 2025; doi: 10.1126/sciadv.adw2464

Oncometabolite 5-IP7 inhibits inositol 5-phosphatase to license E-cadherin endocytosis

Zhang H, Zhang B, Zhao Y, Su Y, Peng Y, Yang X, Zhao H, Liu H, Feng J, Pei H, Zhang W, Huang N, Jiang K, Ito M, Liu G, Jork N, Anderson KE, Zhao L, Nagata E, Jessen HJ, Hawkins PT, Du C, Rao F.

Nat Chem Biol. 2025; doi: 10.1038/s41589-025-02005-z.

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