Emerging principles of primary cilia dynamics in controlling tissue organization and function

Gopalakrishnan J, Feistel K, Friedrich BM, Grapin-Botton A, Jurisch-Yaksi N, Mass E, Mick DU, Müller RU, May-Simera H, Schermer B, Schmidts M, Walentek P, Wachten D.

EMBO J. 2023; doi: 10.15252/embj.2023113891. Online ahead of print.

Cilia are key in sensing signals and rely on the dynamic composition of molecules within the cilium. Cilia dynamically integrate different cellular inputs and control cell fate and function during tissue development. We review the emerging concept of primary cilia dynamics in tissue organization.