Principal Investigators

Prof. Dr. Pitter Huesgen

Prof. Dr. Pitter Huesgen

Kontakt

Prof. Dr. Pitter Huesgen
(he / him)

Institute of Biology II (Faculty of Biology),
University of Freiburg

T +49 761 203 2690
pitter.huesgen(at)biologie.uni-freiburg.de

Weitere Informationen

10 selected publications:

  • Combination of transcriptomic, proteomic and degradomic profiling reveals common and distinct patterns of pathogen-induced cell death in maize.
    Barghahn S#, Saridis G#, Mantz M#, Meyer U, Mellüh JC, Misas Villamil JC, Huesgen PF*, Doehlemann G* (2023)
    The Plant Journal. 2023 Jun 20. doi: 10.1111/tpj.1635.
  • MANTI: Automated Annotation of Protein N-Termini for Rapid Interpretation of N-Terminome Data Sets.
    Demir F*, Kizhakkedathu JN, Rinschen MM, Huesgen PF* (2021)
    Anal Chem 93:5596-5605.
  • Overexpression of human BAG3P209L in mice causes restrictive cardiomyopathy.
    Kimura K, Ooms A, Graf-Riesen K, Kuppusamy M, Unger A, Schuld J, Daerr J, Lother A, Geisen C, Hein L, Takahashi S, Li G, Röll W, Bloch W, van der Ven PFM, Linke WA, Wu SM, Huesgen PF, Höhfeld J, Fürst DO, Fleischmann BK, Hesse M. (2021)
    Nat Commun 12:3575.
  • The mouse heart mitochondria N terminome provides insights into ClpXP-mediated proteolysis
    Hofsetz E, Demir F, Szczepanowska K, Kukat A, Kizhakkedathu J, Trifunovic A*, Huesgen PF* (2020)
    Mol Cell Proteomics 19:1330-1345.
  • ExteNDing proteome coverage with legumain as highly specific digestion protease.
    Soh WT, Demir F, Dall E, Perrar A, Dahms SO, Kuppusamy M, Brandstetter H, Huesgen PF (2020)
    Anal Chem 92:2961-2971.
  • Sensitive determination of proteolytic proteoforms in limited microscale proteome samples.
    Weng SSH, Demir F, Ergin EK, Dirnberger S, Uzozie A, Tuscher D, Nierves L, Tsui J, Huesgen PF*, Lange PF* (2019)
    Mol Cellu Proteomics 18:2335-2347.
    *corresponding authors
  • The fungal effector Pit2 acts as molecular mimicry to suppress plant immunity via an inter-kingdom conserved motif.
    Misas-Villamil J, Mueller AN, Demir F, Meyer U, Breuer M, Dauben H, Win J, Huesgen PF, Doehlemann G. (2019)
    Nat Commun 10:1576.
  • N-Degradomic analysis reveals a proteolytic network processing the podocyte cytoskeleton.
    Rinschen MM*, Hoppe AK, Grahammer F, Kann M, Völker LA, Schurek EM, Binz J, Höhne M, Malisic M, Demir F, Malisic M, Huber TB, Kurschat C, Kizhakkedathu JN, Schermer B, Huesgen PF*, Benzing T* (2017)
    Journal of the American Society of Nephrology 28: 2867-2878.
    *corresponding authors
  • LysargiNase mirrors trypsin for protein C-termini and methylation site identification.
    Huesgen PF, Lange PF, Rogers LR, Solis N, Eckhard U, Kleifeld O, Gomis-Rüth XF, Overall CM (2015)
    Nat Methods 12, 55-8.
  • Proteome-wide Characterization of Protein Carboxy-Termini: C-terminomics.
    Schilling O, Barré O, Huesgen PF, Overall CM (2010)
    Nat Methods 7:508-11.