CIBSS - Centre for integrative Biological Signalling Studies CIBSS

GSG1L-containing AMPA receptor complexes are defined by their spatiotemporal expression, native interactome and allosteric sites

Perozzo AM, Schwenk J, Kamalova A, Nakagawa T, Fakler B, Bowie D.

Nat Commun.2023; doi: 10.1038/s41467-023-42517-7.

Specificity of excitatory synaptic transmission is controlled by the distinct subunit composition(s) of AMPA-receptors. This work demonstrates the particular role of GSG1l in endowing AMPA-receptors with distinct properties in gating and surface dynamics.