CIBSS - Centre for integrative Biological Signalling Studies CIBSS

PUBLICATIONS

CIBSS Publications

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Expanding the Inositol Pyrophosphate Toolbox: Stereoselective Synthesis and Application of PP-InsP4 Isomers in Plant Signaling

Ritter K, Braun AS, Liu G, Lu M, Gaugler V, Schaaf G, Jessen HJ.

Angew Chem Int Ed Engl. 2025 Jul 1:e202507058. doi: 10.1002/anie.202507058. Online ahead of print.

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AhR activation mitigates graft-versus-host disease of the central nervous system by reducing microglial NF-κB signaling

Zähringer A, Morgado I, Erny D, Ingelfinger F, Gawron J, Chatterjee S, Wenger V, Schmidt D, Schwöbel L, Adams RC, Langenbach M, Hartmann A, Osswald N, Wolf J, Schlunck G, Briquez PS, Grueter K, Ruess DA, Frew I, Burk AC, Holzmüller V, Grimbacher B, Michonneau D, Andrieux G, Socié G, Kolter J, Boerries M, Follo M, Blaeschke F, Sevenich L, Prinz M, Zeiser R, Vinnakota JM.

Blood Adv. 2025; doi: 10.1182/bloodadvances.2024015000.

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MCAM is a prognostic biomarker in patients with liver cirrhosis and HCC

Stockinger E, Luxenburger H, Bettinger D, Berlin C, Obwegs D, Sagar, Sturm L, Gromak M, Gairing S J, Foerster F, Labenz C, MacNelly S, Boettler T, Holzner P, Bronsert P, Bengsch B, Thimme R, Hofmann M, Roehlen N.

Hepatol Commun. 2024 Oct 3. doi: 10.1097/HC9.0000000000000532. eCollection 2024 Oct 1.

Beyond genotype: challenges in predicting disease risk for carriers of biallelic perforin variants

Wegehaupt O, Borisov O, Sieni E, Oyen F, Mann J, Coniglio ML, Chinnici A PhD, Pegoraro F, Beneforti L, Gilmour KC, Moshous D, de Saint Basile G, Zhang W, Marsh RA, De Fusco C, Wustrau K, Timeus F, Micalizzi C, Gunsilius E, Hosking L, Choo S, Ghosh S, Köttgen A, Lehmberg K, Ehl S.

Blood. 2025; doi: 10.1182/blood.2024027954.

A Screening Approach Unveils an Unknown Mn2+ dependent Endopolyphosphatase Activity in Yeast

Moser S, Hans G, Shukla A, Saiardi A, Bru A, Taskin AA, Meisinger C, Jessen H

Chem. Sci., 2025, DOI:10.1039/D5SC02166A.

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Synthesis of a New Purine Analogue Class with Antifungal Activity and Improved Potency against Fungal IP3-4K

Desmarini D, Truong D, Sethiya P, Liu G, Bowring B, Jessen H, Dinh H, Cain AK, Thompson PE, Djordjevic JT.

ACS Infect Dis. 2025; doi: 10.1021/acsinfecdis.4c00975

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Neuronal pSTAT1 hallmarks synaptic pathology in autoimmune encephalitis against intracellular antigens

Di Liberto G, Egervari K, Vogrig A, Spatola M, Piccinno M, Vincenti I, Wagner I, Kreutzfeldt M, Endmayr V, Ostertag K, Rahimi J, Vicino A, Pröbstel AK, Meyronet D, Frank S, Prinz M, Hewer E, Brouland JP, de Leval L, Parkkinen L, Draganski B, Desestret V, Dubey D, Pittock SJ, Roemer SF, Dickson DW, Höftberger R, Irani SR, Honnorat J, Du Pasquier R, Merkler D.

Acta Neuropathol. 2025; doi: 10.1007/s00401-025-02882-7.

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A dynamic and multimodal framework to define microglial states

Sankowski R, Prinz M

Nat Neurosci. 2025 May 20. doi: 10.1038/s41593-025-01978-3. Online ahead of print.

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Pools of Independently Cycling Inositol Phosphates Revealed by Pulse Labeling with 18O-Water

Kim GD, Liu G, Qiu D, De Leo MG, Gopaldass N, Hermes J, Timmer J, Saiardi A, Mayer A, Jessen HJ.

J Am Chem Soc. 2025; doi: 10.1021/jacs.4c16206.

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Niche-specific therapeutic targeting of myeloid cells in the central nervous system

Frosch M, Prinz M.

Immunity. 2025; doi: 10.1016/j.immuni.2025.03.016

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