Centre for Integrative Biological Signalling Studies
Cluster of Excellence, University of Freiburg

Dr. Ritwick Sawarkar

Dr. Ritwick Sawarkar

Max-Planck-Institute of Immunobiology and Epigenetics Freiburg

+49 761 5108 378

CIBSS Research Project:

 

10 selected publications:

  • Heat-shock protein 90 controls the expression of cell-cycle genes by stabilizing metazoan-specific host-cell factor HCFC1.
    Antonova A, Hummel B, Khavaran A, Redhaber DM, Aprile-Garcia F, Rawat P, Gundel K, Schneck M, Hansen EC, Mitschke J, Mittler G, Miething C, Sawarkar R (2019).
    Cell Rep. 29(6):1645-1659.e9
  • Nascent-protein ubiquitination is required for heat shock-induced gene downregulation in human cells.
    Aprile-Garcia F, Tomar P, Hummel B, Khavaran A, Sawarkar R (2019).
    Nat Struct Mol Biol. 26(2):137-146.
  • Phytochrome-based extracellular matrix with reversibly tunable mechanical properties.
    Hörner M, Raute K, Hummel B, Madl J, Creusen G, Thomas OS, Christen EH, Hotz N, Gübeli RJ, Engesser R, Rebmann B, Lauer J, Rolauffs B, Timmer J, Schamel WWA, Pruszak J, Römer W, Zurbriggen MD, Friedrich C, Walther A, Minguet S, Sawarkar R, Weber W (2019).
    Adv Mater. 31(12):e1806727.
  • Preparing junior faculty for success.
    Sawarkar R, Scherz-Shouval R, Denzel M, Saarikangas J (2018).
    Science. 361(6399):238.
  • High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidogenic proteins.
    Vincenz-Donnelly L, Holthusen H, Körner R, Hansen EC, Presto J, Johansson J, Sawarkar R, Hartl FU, Hipp MS. (2018)
    EMBO J. pii: e201695841.
  • Chromatin Immunoprecipitation (ChIP) of Heat Shock Protein 90 (Hsp90).
    Yoveva A, Sawarkar R. (2018)
    Methods Mol Biol. 1709: 221-231.
  • The evolutionary capacitor HSP90 buffers the regulatory effects of mammalian endogenous retroviruses.
    Hummel B, Hansen EC, Yoveva A, Aprile-Garcia F, Hussong R, Sawarkar R. (2017)
    Nat Struct Mol Biol. 24(3): 234-242.
  • Hsp90@chromatin.nucleus: an emerging hub of a networker.
    Sawarkar R and Paro R (2013)
    Trends in Cell Biol. 23(4):193-201.
  • Hsp90 globally targets paused RNA polymerase to regulate gene expression in response to stimuli.
    Sawarkar R, Sievers C and Paro R (2012)
    Cell. 149(4):807-18.
  • Interpretation of developmental signaling at chromatin: a Polycomb perspective.
    Sawarkar R and Paro R (2010)
    Dev Cell 19: 651-661.