Centre for Integrative Biological Signalling Studies
Cluster of Excellence, University of Freiburg

PD Dr. Susana Minguet

PD Dr. Susana Minguet

Institute of Biology III - Department of Molecular Immunology (Faculty of Biology)
University of Freiburg

+49 761 203 67514

CIBSS Research Project:

 

10 selected publications:

  • Phytochrome-Based Extracellular Matrix with Reversibly Tunable Mechanical Properties.
    Hörner M, Raute K, Hummel B, Madl J, Creusen G, Thomas OS, Christen EH, Hotz N, Gübeli RJ, Engesser R, Rebmann B, Lauer J, Rolauffs B, Timmer J, Schamel WWA, Pruszak J, Römer W, Zurbriggen MD, Friedrich C, Walther A, Minguet S, Sawarkar R, Weber W (2019).
    Adv Mater. 31(12):e1806727.
  • Caveolin-1: The Unnoticed Player in TCR and BCR Signaling.
    Fiala GJ, Minguet S (2018).
    Adv Immunol. 137:83-133. Caveolin-1-dependent nanoscale organization of the BCR regulates B cell tolerance.
    Minguet S§, Kläsener K, Schaffer AM, Fiala GJ, Osteso-Ibánez T, Raute K, Navarro-Lérida I, Hartl FA, Seidl M, Reth M, Del Pozo MA.
    Nat Immunol. 10:1150-1159. §Corresponding author.
  • The Allostery Model of TCR Regulation.
    Schamel WW, Alarcon B, Höfer T, Minguet S (2017).
    J Immunol. 198(1):47-52.
  • A cholesterol-based allostery model of T cell receptor phosphorylation.
    Swamy M, Beck-Garcia K, Beck-Garcia E, Hartl FA, Morath A, Yousefi OS, Dopfer EP, Molnár E, Schulze AK, Blanco R, Borroto A, Martín-Blanco N, Alarcon B, Höfer T, Minguet S§, Schamel WW (2016).§
    Immunity. 44(5):1091-101.
    §Corresponding authors.
  • Caveolin-1 regulates TCR signal strength and regulatory T cell differentiation into alloreactive T cells
    Schönle A, Hartl FA, Mentzel J, Rauch KS, Wohlfeil SA, Nöltner T, Hechinger AK, Melchinger W, Fehrenbach K, Guadamillas MC, Prestipino A, Follo M, Prinz G, Ruess AK, Pfeifer D, Pozo MA, Schmitt-Graeff A, Duyster J, Blazar BR, Schachtrup K, Minguet S§, Zeiser R§ (2016).
    Blood. 127(15):1930-9.
    §Corresponding authors.
  • Kidins220/ARMS binds to the B cell antigen receptor and regulates B cell development and activation
    Fiala GJ, Janowska I, Prutek, F, Hobeika E, Satapathy A, Sprenger A, Plum T, Seidl M, Dengjel J, Reth M, Cesca F, Brummer T, Minguet S§ and Schamel WWA§ (2015).
    J Exp Med 212(10):1693-708.
    §Corresponding authors.
  • Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastais.
    Goetz JG*, Minguet S*, Navarro I, Samaniego R, Tello M, Calvo E, Lazcano JJ, Osteso T, Pellinen T, Echarri A, Cerezo A, Garcia R, Keely PJ, Sánchez-Mateos P, Cukierman E, Del Pozo MA (2011).
    Cell. (146):148-63.
    *Shared first authorship.
  • Enhanced B cell activation mediated by TLR4 and BCR crosstalk.
    Minguet S§, Huber M, Freudenberg MA, Pollmer C, Reth M, Schamel WW (2008).
    Eur J Immunol. 38(9):2475-87
    §Corresponding author.
  • Full activation of the T cell receptor requires both clustering and conformational changes at CD3.
    Minguet S, Swamy M, Alarcon B, Luescher IF, Schamel WW (2007).
    Immunity. (1): 43-54.