Centre for Integrative Biological Signalling Studies
Cluster of Excellence, University of Freiburg

PD Dr. Thomas Becker

PD Dr. Thomas Becker

Institute of Biochemistry and Molecular Biology (Faculty of Medicine)
University of Freiburg

+49 761 203 5243

CIBSS Research Project:

 

10 selected  publiations:

  • Mitochondrial protein translocation-associated degradation.
    Mårtensson CU, Priesnitz C, Song J, Ellenrieder L, Doan KN, Boos F, Floerchinger A, Zufall N, Oeljeklaus S, Warscheid B, Becker T (2019).
    Nature 569, 679-683.
  • Dual role of mitochondrial porin in metabolite transport across the outer membrane and protein transfer to inner membrane.
    Ellenrieder L, Dieterle MP, Doan KN, Mårtensson CU, Floerchinger A, Campo ML, Pfanner N, Becker T (2019).
    Mol Cell 73, 1056-1057.
  • Recruitment of cytosolic J-proteins by TOM receptors promotes mitochondrial protein biogenesis.
    Opaliński Ł, Song J, Priesnitz C, Wenz LS, Oeljeklaus S, Warscheid B, Pfanner N, Becker T( 2018).
    Cell Rep. 25, 2026-2043.
  • Membrane protein insertion through a mitochondrial beta-barrel gate
    Höhr AIC, Lindau C, Wirth C, Qiu J, Stroud DA, Kutik S, Guiard B, Hunte C, Becker T, Pfanner N, Wiedemann N. (2018).
    Science 359, eaah6834.
  • Separating mitochondrial protein assembly and endoplasmic reticulum tethering by selective coupling of Mdm10.
    Ellenrieder L, Opalinski L, Becker L, Krüger V, Mirus O, Straub SP, Ebell K, Flinner N, Stiller SB, Guiard B, Meisinger C, Wiedemann N, Schleiff E, Wagner R, Pfanner N, Becker T. (2016)
    Nat. Commun. 7, 13021.
  • MOF acetyl transferase regulates transcription and respiration in mitochondria.
    Chatterjee A, Seyfferth J, Lucci J, Gilsbach R, Preissl S, Böttinger L, Mårtensson CU, Panhale A, Stehle T, Kretz O, Sahyoun AH, Avilov S, Eimer S, Hein L, Pfanner N, Becker T, Akhtar A. (2016)
    Cell 167, 722-738.
  • Sam37 is crucial for formation of the mitochondrial TOM-SAM supercomplex, thereby promoting beta-barrel biogenesis. br />Wenz LS, Ellenrieder L, Qiu J, Bohnert M, Zufall N, van der Laan M, Pfanner N, Wiedemann N, Becker T. (2015)
    J. Cell. Biol. 210, 1047-1054.
  • The presequence pathway is involved in protein sorting to the mitochondrial outer membrane.
    Wenz LS, Opalinski L, Schuler MH, Ellenrieder L, Ieva R, Böttinger L, Qiu J, van der Laan M, Wiedemann N, Guiard B, Pfanner N, Becker T. (2014)
    EMBO Rep. 15, 678-685.
  • Coupling of mitochondrial import and export translocases by receptor-mediated supercomplex formation.
    Qiu J, Wenz LS, Zerbes RM, Oeljeklaus S. Bohnert M, Stroud DA, Wirth C, Ellenrieder L, Thornton N, Kutik S, Wiese S, Schulze-Specking A, Zufall N, Chacinska A, Guiard B, Hunte C, Warscheid B, van der Laan M, Pfanner N, Wiedemann N, Becker T. (2013)
    Cell 154, 596-608.
  • Common ground for protein translocation: access control for mitochondria and chloroplasts.
    Schleiff E, Becker T. (2011)
    Nat. Rev. Mol. Cell Biol. 12, 48-59.