Centre for Integrative Biological Signalling Studies
Cluster of Excellence, University of Freiburg

Prof. Dr. Heiko Heerklotz

Prof. Dr. Heiko Heerklotz

Department of Pharmaceutical Technology and Biopharmacy (Faculty of Chemistry and Pharmacy),
University of Freiburg

+49 761 203 6338

CIBSS Research Project:

 

10 selected publications:

  • Engineering asymmetric lipid vesicles: Accurate and convenient ontrol of the outer leaflet lipid composition.
    Markones M, Drechsler C, Kaiser M, Kalie L, Heerklotz H, Fiedler S (2018).
    Langmuir 34:1999-2005
  • Biomembrane permeabilization: Statistics of individual leakage events harmonize the interpretation of vesicle leakage.
    Braun S, Pokorná Š, Šachl R, Hof M, Heerklotz H, Hoernke M (2018).
    ACS Nano 12:813-819
  • Correlating antimicrobial activity and model membrane leakage induced by nylon-3 polymers and detergents
    Hovakeemian SG, Liu R, Gellman SH, Heerklotz H (2015).
    Soft Matter 11:6840-51
  • Characterizing vesicle leakage by fluorescence lifetime measurements.
    Patel H, Tscheka C, Heerklotz H (2009).
    Soft Matter 5:2849-2851
  • Monitoring detergent-mediated solubilization and reconstitution of lipid membranes by isothermal titration calorimetry.
    Heerklotz H, Tsamaloukas A, Keller S (2009).
    Nat Protocols 4:686-697
  • Interactions of surfactants with lipid membranes.
    Heerklotz H (2008).
    Quarterly Reviews of Biophysics 41:205-264
  • Uptake and release protocol for assessing membrane binding and permeation by way of isothermal titration calorimetry.
    Tsamaloukas A, Keller S, Heerklotz H (2007).
    Nat Protocols 2:695-704
  • A quantitative model describing the selective solubilization of membrane domains.
    Keller S, Tsamaloukas , Heerklotz H (2005).
    J Am Chem Soc. 127:11469-11476
  • Structural, volumetric and thermodynamic characterization of a micellar sphere-to-rod transition.
    Heerklotz H, Tsamaloukas A, Kita-Tokarczyk K, Strunz P, Gutberlet T (2004).
    J Am Chem Soc. 126:16544
  • Triton promotes domain formation in ´lipid raft´ mixtures.
    Heerklotz H (2002).
    Biophys. J. 83:2693-2701