Centre for Integrative Biological Signalling Studies
Cluster of Excellence, University of Freiburg

Prof. Dr. Gerd Walz

Prof. Dr. Gerd Walz

Department of Internal Medicine – Renal Division (University Medical Center Freiburg, Faculty of Medicine)

+49 761 270 32500

CIBSS Research Project:

 

10 selected publications

  • CXCL12 and MYC control energy metabolism to support adaptive responses after kidney injury.
    Yakulov TA, Todkar AP, Slanchev K, Wiegel J, Bona A, Gross M, Scholz A, Hess I, Wurditsch A, Grahammer F, Huber TB, Lecaudey V, Bork T, Hochrein J, Boerries M, Leenders J, de Tullio P, Jouret F, Kramer-Zucker A, and Walz G (2018).
    Nat Commun 9, 3660.
  • Cilia‐localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney.
    Viau A, Bienaimé F, Luka K, Todkar AP, Knoll M, Yakulov TA, Hofherr A, Kretz O, Helmstaedter M, Reichardt W, Braeg S, Aschman T, Merkle A, Pfeifer D, Dumit VI, Gubler M-C, Nitschke R, Huber TB, Terzi F, Dengjel J, Grahammer F, Köttgen M, Busch H, Boerries M, Walz G, Triantafyllopoulou A, and Kuehn EW (2018).
    EMBO J doi: 10.15252/embj.201798615.
  • Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors.
    Kaminski MM, Tosic J, Kresbach C, Engel H, Klockenbusch J, Müller AL, Pichler R, Grahammer F, Kretz O, Huber TB, Walz G, Arnold SJ, Lienkamp SS (2016).
    Nat Cell Biol. 18, 1269-1280.
  • mTORC2 critically regulates renal potassium handling.
    Grahammer F, Nesterov V, Ahmed A, Steinhardt F, Sandner L, Arnold F, Cordts T, Negrea S, Bertog M, Ruegg MA, Hall MN, Walz G, Korbmacher C, Artunc F, Huber TB (2016).
    J Clin Invest 126, 1773-1782.
  • The polarity protein Inturned links NPHP4 to Daam1 to control the subapical actin network in multiciliated cells.
    Yasunaga T, Hoff S, Schell C, Helmstädter M, Kretz O, Kuechlin S, Yakulov TA, Engel C, Müller B, Bensch R, Ronneberger O, Huber TB, Lienkamp SS, Walz G (2015).
    J Cell Biol. 211, 963-73.
  • Anks3 interacts with nephronophthisis proteins and is required for normal renal development.
    Yakulov TA, Yasunaga T, Ramachandran H, Engel C, Muller B, Hoff S, Dengjel J, Lienkamp SS, Walz G (2015).
    Kidney Int 87, 1191-1200.
  • TSC1 activates TGF-beta-Smad2/3 signaling in growth arrest and epithelial-to-mesenchymal transition.
    Thien A, Prentzell MT, Holzwarth B, Klasener K, Kuper I, Boehlke C, Sonntag AG, Ruf S, Maerz L, Nitschke R, Grellscheid SN, Reth M, Walz G, Baumeister R, Neumann-Haefelin E, Thedieck K (2015).
    Dev Cell 32, 617-630.
  • Autosomal dominant polycystic kidney disease: the changing face of clinical management.
    Ong AC, Devuyst O, Knebelmann B, Walz G (2015).
    Lancet 385, 1993-2002.
  • ANKS6 is a central component of a nephronophthisis module linking NEK8 to INVS and NPHP3.
    Hoff S, Halbritter J, Epting D, Frank V, Nguyen TM, van Reeuwijk J, Boehlke C, Schell C, Yasunaga T, Helmstadter M, Mergen M, Filhol E, Boldt K, Horn N, Ueffing M, Otto EA, Eisenberger T, Elting MW, van Wijk JA, Bockenhauer D, Sebire NJ, Rittig S, Vyberg M, Ring T, Pohl M, Pape L, Neuhaus TJ, Elshakhs NA, Koon SJ, Harris PC, Grahammer F, Huber TB, Kuehn EW, Kramer-Zucker A, Bolz HJ, Roepman R, Saunier S, Walz G, Hildebrandt F, Bergmann C, Lienkamp SS (2013).
    Nat Genet 45, 951-956.
  • Vertebrate kidney tubules elongate using a planar cell polarity-dependent, rosette-based mechanism of convergent extension.
    Lienkamp SS, Liu K, Karner CM, Carroll TJ, Ronneberger O, Wallingford JB, Walz G (2012).
    Nat Genet 44, 1382-1387.