Centre for Integrative Biological Signalling Studies
Cluster of Excellence, University of Freiburg

Prof. Dr. Maja Köhn

Prof. Dr. Maja Köhn

Institute of Biology III – Integrated Signalling Research (Faculty of Biology)
University of Freiburg

+49 761 203 67900

CIBSS Research Project:

 

10 selected publications

  • Turn and face the strange: A new view on phosphatases.
    Köhn M (2020)
    ACS Cent Sci. DOI:10.1021/acscentsci.9b00909.
  • Molecular mechanism of SHP2 activation by PD-1 stimulation.
    Marasco M, Berteotti A, Weyershaeuser J, Thorausch N, Sikorska J, Krausze J, Brandt HJ, Kirkpatrick J, Rios P, Schamel WW, Köhn M, Carlomagno T (2020)
    Sci Adv. 2020/6: eaay4458.
  • Interrogating PP1 activity in the MAPK pathway with optimized PP1-disrupting peptides.
    Wang Y, Hoermann B, Pavic K, Trebacz M, Rios P, Köhn M (2019).
    Chembiochem. 20(1):66-71.
  • Activation of protein phosphatase 1 by a selective phosphatase disrupting peptide reduces sarcoplasmic reticulum Ca2+ leak in human heart failure.
    Fischer TH, Eiringhaus J, Dybkova N, Saadatmand A, Pabel S, Weber S, Wang Y, Köhn M, Tirilomis T, Ljubojevic S, Renner A, Gummert J, Maier LS, Hasenfuß G, El-Armouche A, Sossalla S (2018).
    Eur J Heart Fail. 20(12):1673-1685.
  • PRL-3 disrupts epithelial architecture by altering the post-mitotic midbody position.
    Luján P, Varsano G, Rubio T, Hennrich ML, Sachsenheimer T, Gálvez-Santisteban M, Martín-Belmonte F, Gavin AC, Brügger B, Köhn M (2016).
    J Cell Sci. 129, 4130-4142.
  • Synthesis of highly selective submicromolar microcystin-based inhibitors of protein phosphatase (PP)2A over PP1.
    Fontanillo M, Zemskov I, Häfner M, Uhrig U, Salvi F, Simon B, Wittmann V, Köhn M (2016).
    Angew Chem Int Ed. 55, 13985-13989.
  • The human DEPhOsphorylation database DEPOD: a 2015 update.
    Duan G, Li X, Köhn M (2015).
    Nucleic Acids Res. 43(Database issue):D531-5.
  • Unnatural amino acid mutagenesis reveals dimerization as a negative regulatory mechanism of VHR's phosphatase activity.
    Pavic K, Rios P, Dzeyk K, Koehler C, Lemke EA, Köhn M (2014).
    ACS Chem Biol. 9, 1451-9.
  • Elucidating human phosphatase-substrate networks.
    Li X, Wilmanns M, Thornton J, Köhn M (2013).
    Sci Signal. 6, 275, rs10.
  • Development of a peptide that selectively activates protein phosphatase-1 in living cells.
    Chatterjee J, Beullens M, Sukackaite R, Qian J, Lesage B, Hart DJ, Bollen M, Köhn M (2012).
    Angew Chem Int Ed. 51, 10054-9.